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Kadcyla 160mg Injection
Salt Composition: ADO-TRASTUZUMAB EMTANSINE
- Manufacturer: ROCHE PRODUCTS INDIA PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 160MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Kadcyla 160mg Injection should be stored in the refrigerator at 2°C to 8°C (36°F to 46°F). Protected from light. Keep it in its original packaging until it is ready to be used. Keep reaching out of the reach of children and pets. It should be disposed of properly.
₹225000.00₹258010.00
Inclusive of all taxes
Product Introduction
Kadcyla 160mg Injection contains the active ingredient ado-trastuzumab emtansine. It is a prescription medication used to treat HER2-positive breast cancer that has spread to other parts of the body or has not responded to other treatments. It is a combination of two drugs: trastuzumab, which is an antibody that targets HER2 receptors, and emtansine, which is a chemotherapy drug that kills cancer cells. It is indicated to treat breast cancer in the early stages as well as advanced stages, where patients develop recurrence within six months of chemotherapy treatment. This medication acts against tumours that produce more than the normal amount of a certain protein known as HER2 protein. Patients with residual breast cancer after chemotherapy treatment and HER2-targeted therapy have a poorer prognosis than those with no residual cancer. Report to your physician immediately if you experience side effects such as allergic reactions or unusual bleeding. This medication does not show any adverse effects on the kidney. In rare cases, an infusion reaction is seen. Like all other medications, it shows mild side effects including nausea, vomiting, diarrhoea, and hair loss.
Uses
Kadcyla Injection uses are as follows: Advanced and metastatic breast cancer Metastatic gastric cancer
How it works
Ado-Trastuzumab emtansine works by combining the targeting ability of trastuzumab, which binds to HER2-positive cancer cells, with the cell-killing effects of emtansine, a chemotherapy drug. Once this medication binds to the HER2-positive cancer cells, it releases emtansine, which then enters the cancer cells and destroys them. This process helps to slow down or stop the growth of cancer, reducing the size of tumours and potentially extending the patient's life.
How to Use
Kadcyla 160mg Injection is administered by a healthcare professional in a hospital or clinic setting. The dose and frequency depend on several factors, such as the individual's age, weight, overall health, and the type and stage of the cancer being treated. If a dose is missed, it should be taken as soon as possible unless it's almost time for the next scheduled dose, in which case the missed dose should be skipped, and the regular dosing schedule resumed. Do not double the dose to make up for missed doses.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Kadcyla 160mg Injection can cause side effects as follows: Serious: Infusion reactions, including fever, chills, rash, or difficulty breathing Lung problems, including shortness of breath, cough, or fever Heart problems, including heart failure or abnormal heart rhythms Severe bleeding or bruising Nerve damage, including numbness, tingling, or weakness Severe allergic reactions Common: Fatigue Nausea Constipation Muscle or joint pain Headache Fever Low platelet count High liver enzyme levels Low red blood cell count Loss of appetite Rash or itching
Expert Tips
If you are receiving Kadcyla 160mg Injection, it's important to be proactive in managing your treatment and monitoring your symptoms. Keep communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Use effective birth control during the treatment and at least 7 weeks after the last dose. Immediately contact your healthcare provider in case of any worsening of symptoms or infusion reactions. Take steps to care for yourself physically and emotionally during treatment, and seek support from loved ones and professionals as needed. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. Being informed and engaged in your treatment can help ensure the best possible outcomes and manage potential risks or complications.
References
- Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 9th April 2023], https://www.medicines.org.uk/emc/files/pil.5252.pdf
- Gunter von Minckwitz et al., Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer, N Engl J Med 2019; 380:617-628 [Accessed on 19th April 2023], https://www.nejm.org/doi/full/10.1056/NEJMoa1814017
- Barok et al., Trastuzumab emtansine: mechanisms of action and drug resistance, Breast Cancer Research 2014, 16:209, [Accessed on 19th April 2023], https://www.researchgate.net/publication/262780064_Trastuzumab_emtansine_Mechanisms_of_action_and_drug_resistance
- Genentech, Inc. U.S Food and Drug Administration (FDA) [Last Revised 3rd May 2019], [Accessed on 19 April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/125427s105lbl.pdf
Safety Advice
Pregnancy: unsafe Discuss with your physician before taking this Kadcyla 160mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause harm to the unborn baby.
Lungs: Consult your doctor Kadcyla 160mg Injection safety and efficacy have not been extensively studied. So, patients with pre-existing lung conditions should consult a doctor before taking it.
Breastfeeding: unsafe Avoid breastfeeding your baby while on the treatment with Kadcyla 160mg Injection for at least seven months after the final dose.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.