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Karplat 450mg Injection

Salt Composition: CARBOPLATIN

₹1954.00₹2791.53

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Karplat 450mg Injection is an alkylating agent anti-cancer medicine containing Carboplatin. It is used to treat certain types of ovarian and lung cancer, either as monotherapy or in combination with other medications.

Monitor for symptoms of allergic reactions, abnormal bruising, kidney problems (haemolytic-uraemic syndrome), and decrease in red blood cells (anaemia). Report any lung-related symptoms to your doctor, including shortness of breath, lung tissue inflammation, or lung infection while taking Karplat 450mg Injection.

Patients receiving this medication should use effective contraception and continue contraceptive use for six months following the final dose. Karplat 450mg Injection may reduce fertility temporarily or permanently in both men and women. Discuss fertility concerns with your doctor prior to treatment.

Uses

Karplat 450mg injection treats ovarian and lung cancer.

How it works

Karplat 450mg injection acts as an alkylating agent. This medication reduces the proliferation of cells by inhibiting the formation of DNA, RNA, and proteins, which stops DNA replication and results in programmed cell death.

How to Use

Karplat 450mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects

Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them. Common side effects of Karplat 450mg Injection include: Loss of taste Diarrhea Constipation Hair loss Skin rashes & itchiness Kidney problems Extreme tiredness Weakness Inflammation in lung tissues Tingling or numbness in hands, arms, or legs Prickling sensation Breathing difficulties Serious side effects of Karplat 450mg Injection include: Decrease in the number of red blood cells (anaemia) Allergic reactions Abnormal bruising Kidney problems (haemolytic-uraemic syndrome) Hearing problems Signs of infection

Expert Tips

Discuss your fertility concerns with your doctor, as both men and women may experience temporary or permanent fertility reductions while receiving Karplat 450mg injection. If you experience any side effects, contact your doctor immediately. Avoid using Cisplatin or any other anti-cancer medications during Karplat 450mg treatment. Notify your doctor if you have recently received or plan to receive a yellow fever vaccination, or if you are taking any other medications. Do not use Karplat 450mg during a severe asthma attack, and monitor asthma patients closely during treatment. Consult your doctor if you have a history of asthma. Do not use if you are allergic to carboplatin or any of its components.

References

  1. Hospira UK Limited, Electronic medicines compendium (EMC), [Revised on Oct 2021], [Accessed on 22nd Feb 2023], https://www.medicines.org.uk/emc/files/pil.3787.pdf
  2. Teva Parenteral Medicines, Inc, U.S Food & Drug Administration FDA, [Revised on Oct 2011,[Accessed on 22nd Feb 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/077139Orig1s016lbl.pdf
  3. Wim J. F. van der Vijgh et.al; Clinical Pharmacokinetics of Carboplatin; [Published online on 09 Nov 2012];[Accessed on 22nd Feb 2023]; https://link.springer.com/article/10.2165/00003088-199121040-00002

Safety Advice

Pregnancy: unsafe Karplat 450mg injection is unsafe to use during pregnancy as it may cause harmful effects on the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment.

Lungs: Consult your doctor Consult your doctor if you experience any liver disease while taking this treatment. Patients with liver disease should cautiously use Karplat 450mg injection.

Breastfeeding: unsafe Taking Karplat 450mg injection while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS