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Kaviox 500mg Injection

Salt Composition: AVIBACTAM

₹1069.00₹1405.31

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Kaviox 500mg Injection contains Avibactam, a non-β-lactam β-lactamase inhibitor belonging to the pharmacological class of beta-lactamase inhibitors. It is used in combination with other antibiotics, such as ceftazidime, to treat resistant bacterial infections. Avibactam inhibits certain β-lactamases produced by resistant bacteria, restoring the efficacy of antibiotics. Therapeutically, Kaviox 500mg Injection is classified as an antibacterial agent, particularly effective against multidrug-resistant Gram-negative bacteria. It is indicated for treatment of complicated intra-abdominal infections (cIAIs), complicated urinary tract infections (cUTIs), and hospital-acquired bacterial pneumonia (HABP) in patients. Patients with renal impairment, pregnancy, or a history of severe allergic reactions to antibiotics require healthcare provider assessment prior to use. The product should only be administered under medical supervision to ensure safety and efficacy.

Uses

Treatment of complicated intra-abdominal infections (cIAIs) Management of complicated urinary tract infections (cUTIs), including pyelonephritis Treatment of hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) Effective against infections caused by carbapenem-resistant Enterobacteriaceae (CRE)

How it works

Avibactam works by inhibiting specific β-lactamases, enzymes that bacteria produce to resist antibiotics. This inhibition allows the partner antibiotic, such as ceftazidime, to remain effective against the bacteria. Avibactam does not possess antibacterial activity on its own but enhances the efficacy of β-lactam antibiotics by neutralizing bacterial resistance mechanisms. This dual-action helps in managing infections caused by multidrug-resistant organisms, ensuring better clinical outcomes.

How to Use

Recommended dosage is based on patient weight and infection severity; follow the doctor’s prescription. Typically administered intravenously over 2 hours in a hospital setting. Kaviox 500mg Injection is given in combination with ceftazidime for optimal efficacy.

Side Effects

Common side effects : Nausea Diarrhea Headache Abdominal pain Serious side effects : Severe allergic reactions (rash, swelling, or difficulty breathing) Kidney impairment Clostridioides difficile-associated diarrhea Seizures (rare)

Expert Tips

Patients should complete the prescribed course to prevent antibiotic resistance. Avoid self-medicating or discontinuing treatment without consulting a doctor. Regular monitoring of kidney function is advised for patients with renal issues. Stay hydrated and adhere to medical recommendations for optimal recovery.

References

  1. https://go.drugbank.com/drugs/DB09060
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Avibactam
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC4187909/
  4. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/avibactam

Safety Advice

Pregnancy: Consult your doctor Limited data is available regarding the use of Kaviox 500mg Injection in pregnant women. It should only be used if the potential benefits outweigh the risks to the fetus, and always under strict medical supervision. If you are pregnant or planning to conceive, consult your doctor before starting this medication.

Lungs: safe There are no direct adverse effects of Kaviox 500mg Injection on lung function. It can be safely used in patients without pre-existing severe respiratory conditions. Always inform your doctor if you have any respiratory issues before starting the treatment.

Breastfeeding: unsafe Kaviox 500mg Injection may pass into breast milk, posing potential risks to nursing infants. It is generally advised to avoid breastfeeding while on this medication unless deemed essential by your doctor. Discuss alternative feeding methods or options with your healthcare provider during treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS