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Kezone-S 2gm Injection

Salt Composition: CEFOPERAZONE,SULBACTAM

₹449.00₹560.63

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antibacterials

Product Introduction

Kezone-S 2gm Injection contains two active ingredients: Cefoperazone, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor. This combination provides activity against a broad spectrum of bacteria and is used to treat serious infections including urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.

The injection is contraindicated in patients with known hypersensitivity or allergy to Cefoperazone, Sulbactam, or any component of the formulation. Inform your doctor if you are allergic to any antibiotic group.

Consumption of alcohol (including alcoholic beverages, alcohol-containing medications, mouthwashes, or food preparations) during administration and up to five days after treatment can cause a disulfiram-like reaction, characterised by flushing, sweating, headache, and increased heart rate. Avoid alcohol during this period.

Notify your doctor if you experience severe or bloody stools while taking this injection. Before treatment, inform your doctor if you have liver disorders, bowel diseases, or clotting disorders.

Use during pregnancy only when necessary. This medicine passes poorly into breast milk; exercise caution during breastfeeding. Consult your doctor for further advice.

Uses

Respiratory Tract Infections Urinary Tract Infections Intra-abdominal Infections Septicemia Meningitis Skin and Soft Tissue Infections Bone and Joint Infections Endometritis

How it works

Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.

How to Use

Do not self-administer the Kezone-S 2gm injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion or intramuscular Injection, and you will be monitored carefully for unwanted side effects.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Nausea, vomiting Headache Diarrhea Allergic reactions Anemia Abnormal liver function Injection site reactions

Expert Tips

Maintaining good hand hygiene by washing your hands regularly helps to prevent the spread of infections to others. Do not skip doses or stop the medication suddenly, even if you start feeling better. Completing the full course of treatment is important to effectively treat the infection and prevent the development of antibiotic resistance.

References

  1. Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
  2. Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
  4. KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.

Safety Advice

Pregnancy: Consult your doctor Kezone-S 2gm injection should be taken if it is necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment.

Lungs: safe Kezone-S 2gm injection is safe and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Kezone-S 2gm injection because the medicine passes into the breast milk in small amounts and harms the baby. Caution is advised in these conditions.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS