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Kintsugi 440mg Injection
Salt Composition: TRASTUZUMAB
- Manufacturer: MANKIND PHARMACEUTICALS LIMITED
- Pack Size: 1 VIAL(s) OF 20ML
- Dosage Form: INJECTION
- Strength: 440MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Keep Kintsugi 440mg Injection out of sight and reach of children. Store between 2ËC and 8ËC.
₹16758.00₹22982.80
Inclusive of all taxes
Product Introduction
Kintsugi 440mg Injection contains Trastuzumab as the active ingredient and is indicated for HER2-positive breast cancer. In patients with HER2-positive breast cancer, cancer cells express elevated levels of HER2 proteins, which promote rapid tumour development through signal transduction in malignant cells. This medication is also used to treat metastatic gastric cancer with elevated HER2 protein expression. HER2-positive breast cancers are typically more aggressive. The targeted therapy mechanism works by selectively binding to HER2 proteins responsible for cancer cell growth, proliferation, and metastasis. Effective contraception must be used during treatment and for at least 7 months following the final dose. Kintsugi 440mg Injection is not recommended for patients under 18 years of age, or those with severe respiratory compromise requiring oxygen supplementation. Inform your physician of any cardiac conditions, dyspnoea, or prior cancer treatments. Disclose all medications, supplements, and herbal preparations to your physician prior to initiating treatment with this medication.
Uses
Kintsugi 440mg Injection is indicated for its use in the following conditions: Advanced and metastatic breast cancer Metastatic gastric cancer
How it works
The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Kintsugi 440mg Injection selectively binds to HER2 and stops the growth of cancer cells.
How to Use
Kintsugi 440mg Injection shall either be administered before or after surgery. It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. The side effects of Kintsugi 440mg Injection are listed below: Common: Heart Problems (Serious) Allergic reactions (Serious) Kidney problems (Serious) Breathing difficulties (Serious) Fever Visual disturbances Nose bleeds or runny nose Hair loss Dizziness Nail disorders Weight loss Loss of appetite Bruising Dry mouth Liver inflammation Muscle pain Asthma/ lung disorders
Expert Tips
It is suggested to inform your doctor if you have a history of allergic reactions to trastuzumab to avoid life-threatening complications. If you have a history of lung disorder or breathing problems inform your doctor beforehand before the treatment commencement. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during the treatment with Kintsugi 440mg Injection as it may impact the functioning of the heart.
References
- Roche, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 12th July 2022], https://www.medicines.org.uk/emc/files/pil.3856.pdf
- Genentech Inc, [Revised on Feb 2021] [Accessed on 12th July 2022], https://www.gene.com/download/pdf/herceptin_prescribing.pdf
- Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilmanâs Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.
Safety Advice
Pregnancy: Consult your doctor Discuss with your physician before taking this Kintsugi 440mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take it as it may cause to the unborn baby.
Lungs: Consult your doctor You need to tell your physician if you have any lung disorders before starting Kintsugi 440mg Injection, as this medication should be used with caution in patients with lung disorder.
Breastfeeding: unsafe Avoid breastfeeding your baby while on the treatment with Kintsugi 440mg Injection at least for at least seven months after the final dose.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.