Kyzific 40mg Tablet

Kyzific 40mg tablet contains asciminib, an anticancer medicine belonging to the class of tyrosine kinase receptor inhibitors. Kyzific 40mg tablet is used to treat chronic myeloid leukaemia (CML), a type of cancer of the white blood cells, in chronic phase in patients who have received prior treatment with two or more tyrosine kinase inhibitors. It works by inhibiting the BCR-ABL1 tyrosine kinase, a fusion protein resulting from the Philadelphia chromosome translocation in chronic myeloid leukaemia (CML). It binds specifically to the myristoyl pocket of the ABL1 domain within the BCR-ABL1 protein, inducing a conformational change that locks the protein in an inactive state and inhibits its oncogenic activity. Inform your doctor before starting treatment with Kyzific 40mg tablet, as it may cause blood problems such as low platelet and white blood cell counts, pancreatic issues, and high blood pressure. Ensure you inform your physician of all medicines you are taking before beginning treatment with this medication. Report any symptoms of difficulty breathing together with a cough or fever, chest pain, fever, weakness, or seizures.

To treat a certain type of chronic myeloid leukaemia (CML; a type of cancer of the white blood cells) in a chronic phase (CP) who have been previously treated with two or more tyrosine kinase inhibitors.

Kyzific works by binding specifically to the myristoyl pocket of the ABL1 domain within the BCR-ABL1 protein, inducing a conformational change that locks the protein in an inactive state and inhibits its oncogenic activity.

Take Kyzific 40mg tablet exactly as your doctor tells you. Do not change your dose or schedule or stop taking Kyzific 40mg tablet unless your healthcare provider tells you to. Take Kyzific 40mg tablet without food. You should avoid eating for at least 2 hours before and 1 hour after taking the Kyzific 40mg tablet. Swallow Kyzific 40mg tablets whole. Do not break, crush, or chew tablets.

Like all medications, Kyzific 40 mg tablet can cause side effects, although not everyone who takes it will experience them. Common Upper respiratory tract infection Headache and nausea Tiredness Rashes Muscle, bone or joint pain Diarrhea Rare Trouble breathing or swallowing Swelling of the face, lips, or tongue Fever Skin rash or flushing of your skin Fast heartbeat Severe Pancreatitis

If you are taking any laboratory tests, tell your doctor that you are taking Kyzific 40 mg tablet. It may cause changes in test results or affect the interpretation of certain lab findings. It may also increase your blood pressure. You may be asked to monitor your blood pressure frequently while taking this medication. Please let your doctor know if you notice any changes in your blood pressure.