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Larinate 200 Kit Tablet
Salt Composition: ARTESUNATE,SULPHADOXINE,PYRIMETHAMINE
- Manufacturer: IPCA LABORATORIES LTD
- Pack Size: 6 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Prescription Required
- Storage: Keep out of reach of children and pets. Store in the original packaging to protect from moisture. Avoid direct sunlight Store Larinate 200 Kit Tablet at room temperature.
₹328.00₹408.75
Inclusive of all taxes
Product Introduction
Larinate 200 Kit Tablet contains the active ingredients Artesunate, Sulphadoxine, and Pyrimethamine. It is an antimalarial medication used to treat uncomplicated malaria caused by Plasmodium falciparum. This combination works effectively in areas with high resistance to other antimalarial drugs, overcoming resistance and improving treatment outcomes. Larinate 200 Kit Tablet works by targeting different stages of the malaria parasite's lifecycle. Artesunate generates reactive oxygen species that damage the parasite's cell membranes. Sulphadoxine inhibits folate synthesis, while Pyrimethamine blocks another enzyme crucial to the parasite's DNA production. This multi-target approach makes it more effective than single-drug treatments. Larinate 200 Kit Tablet is used to treat uncomplicated Plasmodium falciparum malaria. Do not use it if you are allergic to any of the components, or if you have liver, kidney, or blood disorders, or if you are pregnant or breastfeeding. Inform your doctor about any history of G6PD deficiency, as this may increase the risk of haemolysis. Common side effects include nausea, vomiting, headache, dizziness, and fatigue. Serious side effects may include severe allergic reactions, liver damage, and blood disorders. If you experience difficulty breathing, persistent fever, severe rash, or unusual bruising or bleeding, seek medical help immediately. Always follow your healthcare provider's instructions for dosage and proper use.
Uses
The uses of the Larinate 200 Kit Tablet are: Treatment of uncomplicated malaria caused by Plasmodium falciparum. Helps overcome drug resistance in malaria infections. Effective in areas with high resistance to other antimalarial medications.
How it works
The Larinate 200 Kit Tablet works to treat malaria. Artesunate generates reactive oxygen species that damage the parasiteâs membranes. Sulphadoxine blocks dihydropteroate synthetase, inhibiting folate synthesis, while Pyrimethamine targets dihydrofolate reductase, disrupting the parasiteâs DNA production. By interfering with these critical metabolic pathways, the combination effectively kills the malaria parasite.
How to Use
The Larinate 200 Kit Tablet contains three antimalarial medicines: Artesunate, Sulphadoxine, and Pyrimethamine. This combination is used to treat malaria, especially in areas with resistant strains. For the correct dose and duration, consult a healthcare professional, as it depends on individual factors like the severity of infection and patient condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them. Common side effects of Larinate 200 Kit Tablet are Diarrhoea Headache Rash Dizziness Nausea Vomiting Abdominal pain Fatigue Serious side effects of Larinate 200 Kit Tablet are: Skin reactions (e.g., blistering, peeling) Blood disorders (e.g., low blood cell counts, anaemia) Seizures or convulsions Liver damage (elevated liver enzymes) Heart problems (e.g., abnormal heart rhythms) Severe allergic reactions (e.g., swelling, difficulty breathing)
Expert Tips
Always follow the prescribed dosage and complete the full course of treatment with Larinate 200 Kit Tablet. Use caution if you have liver or kidney issues, blood disorders, or G6PD deficiency, and consult your healthcare provider if pregnant or breastfeeding. Monitor for side effects and seek immediate medical attention if severe allergic reactions or other serious issues occur. Always consult your doctor before starting the medication, especially if you have underlying health conditions.
References
- 1. Elamin SB, Malik EM, Abdelgadir T, Khamiss AH, Mohammed MM, Ahmed ES, Adam I. Artesunate plus sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum malaria in Sudan. https://pmc.ncbi.nlm.nih.gov/articles/PMC1242247/ 2. Ruwizhi N, Maseko RB, Aderibigbe BA. Recent Advances in the Therapeutic Efficacy of Artesunate. Pharmaceutics. https://pmc.ncbi.nlm.nih.gov/articles/PMC8951414/ 3. Bell DJ, Nyirongo SK, Mukaka M, Zijlstra EE, Plowe CV, Molyneux ME, Ward SA, Winstanley PA. Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi. https://pmc.ncbi.nlm.nih.gov/articles/PMC2229666/ function in the central nervous system. https://pubmed.ncbi.nlm.nih.gov/16806306/
Safety Advice
Pregnancy: Consult your doctor It is unknown if Larinate 200 Kit Tablet are safe to take during pregnancy. Please consult your healthcare provider if you have any concerns.
Lungs: Consult your doctor If you have any pre-existing lung conditions, discuss them with your doctor before starting treatment with Larinate 200 Kit Tablet.
Breastfeeding: Consult your doctor It is unknown if Larinate 200 Kit Tablet are safe to take during breastfeeding. Please consult your healthcare provider if you have any concerns.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.