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Lazid E Kit Tablet
Salt Composition: EFAVIRENZ,LAMIVUDINE,ZIDOVUDINE
- Manufacturer: EMCURE PHARMACEUTICALS LTD
- Pack Size: 1 KIT
- Dosage Form: TABLET
- Strength: 600MG+150MG+300MG
- Prescription Required
- Storage: Store Lazid E Kit Tablet at (20°C to 25°C). Keep the medicine out of reach of children and pets.
₹73.00₹100.79
Inclusive of all taxes
Product Introduction
Lazid E Kit Tablet contains Efavirenz + Lamivudine + Zidovudine, a combination of three antiretroviral medicines. Lamivudine and Zidovudine are nucleoside/nucleotide reverse transcriptase inhibitors. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. This medicine is indicated for treatment of HIV-1 infection, which develops when the human immunodeficiency virus attacks and weakens a person's immune system. Progressive weakening of immune function increases susceptibility to opportunistic infections.
This medicine is contraindicated in patients with severe renal impairment, as altered drug clearance may compromise both efficacy and safety. Dose adjustment is necessary in such conditions.
Inform your doctor before taking Lazid E Kit Tablet if you have liver disease (including hepatitis B or C), kidney disease, heart problems, diabetes, history of seizures, mental health conditions, or a history of street drug use or heavy alcohol consumption.
Administration of this medicine is associated with hematologic toxicity (reduction in blood cell counts), muscle weakness, liver disease, infection, and lactic acidosis (metabolic acid buildup). Do not breastfeed during treatment. Discuss safe sex practices with your doctor.
During initial treatment stages, some patients with HIV may experience immune reconstitution syndrome—an inflammatory response to opportunistic infections that can occur after starting this or other antiretroviral therapies. Monitor for signs of worsening infections or inflammatory symptoms. Inform your healthcare provider if symptoms are concerning or persist beyond the expected duration.
Report any skin reactions or hypersensitivity reactions to your healthcare provider. Seek immediate medical attention for symptoms of severe allergic reaction.
Inform your doctor immediately of all medications, herbal preparations, and supplements you are currently taking before beginning Lazid E Kit Tablet.
Uses
HIV-1 Infection
How it works
Lazid E Kit Tablet is a combination of three antiretroviral medicines. It works by inhibiting the enzyme reverse transcriptase, thereby inhibiting the replication of viral particles in the body and treating the infection.
How to Use
Take the Lazid E Kit Tablet as advised by your physician. Swallow the tablets whole and intact. This tablet should be taken with food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the medicine if your doctor advises you to stop.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, and drowsiness) Liver problems (yellowing of skin or eyes, tea-colored urine, light-colored stools, abdominal pain) Nervous system symptoms (trouble-concentrating, sleeping, unusual dreams, lack of coordination) Hypersensitive reactions Seizures Changes in body fat Muscle pain or weakness Blood problems (low number of white blood cells) Common Nausea, vomiting Headache, dizziness Tiredness Fever or chills Diarrhea Cough Decreased appetite
Expert Tips
Do not share personal objects such as toothbrushes or razors with anyone. To prevent the spread of HIV infection, avoid sharing needles or syringes, which can transmit the infection easily. It's necessary for individuals who use injectable drugs to use sterile needles and syringes and never share them with others. Personal items should also be avoided. They should not be shared because HIV-1 can be present in blood and certain body fluids, and sharing these items could mainly transmit the virus. Since this drug is unsafe for breastfeeding because HIV infection can be passed to the baby in the breast milk, alternative feeding methods can be followed to nourish the infant's growth. If you forget to take Lazid E Kit Tablet for the entire day, take your usual dose the next day. However, do not double-dose yourself. Throw away medicines that are no longer needed or are out-of-date. Keep medicines away from children and pets. Do not store these medicines in a damp place such as a bathroom, cabinet, or near the kitchen sink.
References
- Strides Arcolab Limited, US Food and Drug Administration, [ Issued on May 2007] [ Accessed on 19th May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022096PI.pdf
- Cipla Ltd, [ Revised on July 2020] [ Accessed on 19th May 2023], https://www.ciplamed.com/content/duovir-e-kit
- KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 806 - 811.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1632-1634.
Safety Advice
Pregnancy: unsafe Lazid E Kit Tablet may cause harm to an unborn baby. Inform your doctor if you are pregnant or planning to get pregnant before taking this tablet. The doctor will explain the potential risks and benefits.
Lungs: unsafe It is unknown whether Lazid E Kit Tablet is safe for lung disease patients. Inform your physician if you have any lung diseases before initiating the therapy.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Lazid E Kit Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.