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Leevarin 15mg Tablet
Salt Composition: LEUCOVORIN CALCIUM
- Manufacturer: ADMAC LIFE SCIENCES
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 15MG
- Prescription Required
- Storage: Store Leevarin 15mg Tablet at room temperature (25°C) keep the tablets away from the reach of children and pets. If you forgot to take a dose, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.
₹325.00₹507.78
Inclusive of all taxes
Product Introduction
Leevarin 15mg Tablet contains leucovorin calcium, a substance chemically related to folic acid. Methotrexate, a medicine used in the treatment of cancer and other conditions, can reduce folic acid levels in the body. This medicine is used to counteract the effects of methotrexate and help restore folic acid levels—a process known as leucovorin rescue. It is also used to treat megaloblastic anaemia resulting from reduced folic acid levels.
Do not take Leevarin 15mg Tablet if you are allergic to leucovorin calcium or any other ingredient in this medicine, or if you have certain types of anaemia such as pernicious anaemia or megaloblastic anaemia associated with vitamin B12 deficiency.
Before starting treatment, inform your physician if you have anaemia, kidney problems, heart problems, or liver problems. Notify your physician if you experience wheezing, trouble breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue.
Uses
Methotrexate overdose and toxicity Diminish the counter effects of methotrexate Megaloblastic anemia
How it works
Methotrexate is a folate antagonist that inhibits the enzyme dihydrofolate reductase in cells. Leevarin 15mg Tablet is a folate derivative that does not require reduction by the enzyme dihydrofolate reductase before being used in DNA synthesis. Leucovorin, in contrast, can increase the therapeutic effect and toxicity of 5 fluoropyrimidines, such as 5-fluorouracil, by increasing the drug's binding. It protects healthy cells from the effects of methotrexate or similar medications.
How to Use
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. It is important to take your medicine at the same time every day.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Diarrhea Nausea Vomiting Inflammmed and sore mouth Tiredness Serious Allergic reactions
Expert Tips
If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. If you accidentally take too much Leevarin 15mg Tablet, contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.
References
- Calcium Folinate 15mg Tablets - Summary of Product Characteristics (SmPC) [Internet]. (emc). 2020 [cited 2023 Apr 4]. Available from: https://www.medicines.org.uk/emc/product/6343/smpc
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Drug toxicity and poisoning, 12th edition, 2011, 86.
- KD Tripathi, Essentials of Medical Pharmacology, Haematinics and erythropoietin, 7th edition, 2013, 611.
Safety Advice
Pregnancy: Consult your doctor There is a limited number of studies on the safety of Leevarin 15mg Tablet during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Lungs: Consult your doctor It is unknown whether Leevarin 15mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: Consult your doctor Limited information is available on Leevarin 15mg Tablet safety during breastfeeding. Inform your physician if you are planning to breastfeed.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.