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Lefno 20mg Tablet

Salt Composition: LEFLUNOMIDE

₹273.00₹302.77

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Lefno 20mg Tablet

Categories: Gastroenterology

Conditions: Arthritis

Product Introduction

Lefno 20mg Tablet is an antirheumatic medication belonging to the class of disease-modifying antirheumatic drugs (DMARDs). The active ingredient is Leflunomide. Lefno 20 is indicated for treatment of rheumatoid arthritis, a chronic inflammatory condition affecting the joints. It is also used for psoriatic arthritis, an inflammatory arthritis that develops in some patients with psoriasis. Psoriatic arthritis affects the joints and may cause pain, swelling, stiffness, and restricted range of motion. Lefno Tablet is contraindicated in patients with known hypersensitivity or allergy to Leflunomide or its components. Prior to starting Lefno 20mg Tablet, inform your doctor if you have a history of interstitial lung disease, tuberculosis, skin ulcers, unexplained chronic diarrhoea, or liver and kidney disorders. Your doctor may conduct appropriate investigations and prescribe a reduced dose if required. Certain vaccinations are not recommended during treatment with this medication as it may affect immune system function, potentially compromising vaccine efficacy or safety. This drug persists in the body for an extended period following discontinuation. Therefore, discuss vaccination schedules with your doctor before beginning treatment. If you currently have a severe infection, initiation of Lefno 20mg Tablet treatment may need to be deferred until the infection resolves. Lefno 20mg Tablet is contraindicated in pregnancy as it may cause fetal harm and may pass into breast milk. Concurrent alcohol consumption whilst taking this medication can increase hepatic stress and risk of liver toxicity or other adverse effects. Alcohol use during treatment is therefore not advised.

Uses

Lefno 20 tablet uses are: Treatment of rheumatoid arthritis Treatment of psoriatic arthritis

How it works

Tab Lefno 20 works by suppressing the immune system and reducing inflammation. It inhibits the activity of certain immune cells called lymphocytes, which are involved in the inflammatory process.

How to Use

Take the Lefno 20mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Lefno 20 side effects are: Serious Serious allergic reactions (difficulty breathing, feeling dizzy or light-headed, weakness) Skin rash or ulcers in the mouth, bruising, pale skin Yellow discoloration of eyes and skin, abdominal pain Infections (fever, sore throat, cough) Tingling or pain in hands or feet Common Loss of appetite, weight loss Low white blood cells Mild increase in blood pressure Diarrhea Nausea, vomiting Hair loss Dry skin, itching

Expert Tips

This medication aims to reduce joint pain, swelling, and stiffness. It may take several weeks or months to experience the full benefits of Lefno 20mg Tablet, so be patient and continue taking it as directed.

References

  1. Aspire Pharma Ltd, Electronic medicines compendium (EMC), [Revised on June 2022] [ Accessed on 17th August 2023], https://www.medicines.org.uk/emc/files/pil.5399.pdf
  2. Sanofi-aventis US LLC, US Food and Drug Administration, [Revised on July 2011] [ Accessed on 17th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020905s022lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1014.
  4. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 212.

Safety Advice

Pregnancy: Consult your doctor If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Lefno 20mg Tablet.

Lungs: Consult your doctor It is unknown whether Lefno 20 is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: unsafe Taking Lefno 20mg Tablet while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS