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Lenabenz 5mg Capsule

Salt Composition: LENALIDOMIDE

₹1116.00₹1482.86

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Lenabenz capsule is an immunomodulatory agent containing lenalidomide. It is indicated for the treatment of adults with multiple myeloma, mantle cell lymphoma, myelodysplastic syndrome and follicular lymphoma. Multiple myeloma is a malignancy of plasma cells that proliferate abnormally in the bone marrow. These cells accumulate in the bone marrow and divide uncontrollably. While this malignancy cannot be cured, symptom management is possible. Myelodysplastic syndrome encompasses a group of blood and bone marrow disorders characterised by abnormal blood cells that do not function adequately. Mantle cell lymphoma is a less common malignancy affecting the lymph nodes. Follicular lymphoma is a slow-growing malignancy affecting B cells.

Common side effects associated with Lenabenz capsule include nausea, diarrhoea, constipation, muscle cramps, tiredness, fever, cough, headache, back pain, breathlessness, rashes and thyroid and skin problems. Inform your doctor if any of these side effects occur or persist. Notify your doctor of any allergic reactions to Lenabenz capsule or its ingredients.

Before commencing treatment with this medication, inform your physician if you have a history of blood clots, heart attack, smoking, high blood pressure or elevated cholesterol levels. Inform your physician if you have viral infections such as hepatitis B, varicella zoster or HIV. Regular blood tests will be conducted before and during treatment as this medication may cause a reduction in blood cell counts. This medicine is not recommended for children below 18 years of age.

Uses

Multiple myeloma, myelodysplastic syndrome Mantle cell lymphoma Follicular lymphoma

How it works

Lenabenz capsule activates T cells and natural killer cells of the immune system and facilitates the attack on cancer cells. It works by antagonizing the growth of blood vessels in the cancer cells and delays the development of cancer cells. It inhibits growth and multiplication of tumor cells.

How to Use

Swallow the capsule whole with water. This capsule shall be consumed with or without food. Avoid crushing, chewing or breaking them.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Severe allergic reactions High risk of secondary cancer Liver toxicity Blurred vision Difficulty speaking Faster heartbeat Chest pain or leg pain Swelling in the ankles Dizziness Unusual bleeding or bruising Blood clot formation Common: Tiredness Neutropenia Constipation Diarrhea Muscle cramps Anaemia Fever Back pain Nausea Upper respiratory tract infection Breathlessness Tremor Rash Cough Headache Thyroid problems Dehydration Skin problems

Expert Tips

Male patients are advised to use effective contraception (condom) during treatment with Lenabenz capsule and for 7 days at the end of the treatment even if you have undergone vasectomy. They should not donate sperm because this medication is present in the semen. It is advised not to donate blood during therapy and for at least 7 days after treatment.

References

  1. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  2. Bristol-Myers Squibb Pharma EEIG, Electronic Medicines Compendium (EMC), [Revised on Nov 2020] [Accessed on 23 Nov 2022], https://www.medicines.org.uk/emc/files/pil.10046.pdf
  3. Celgene Corporation, US Food & Drug Administration, [Revised on Jun 2013] [Accessed on 23 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/021880s034lbl.pdf

Safety Advice

Pregnancy: unsafe Lenabenz capsules are unsafe to use during pregnancy as they might be harmful to an unborn child. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.

Lungs: Consult your doctor Inform your physician before starting this treatment if you have kidney diseases. Your physician might adjust the dose accordingly.

Breastfeeding: unsafe Lenabenz capsule is probably unsafe to use during breastfeeding as it is not known if this medication passes into breast milk and harms your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS