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Lenceliv 10mg Capsule

Salt Composition: LENVATINIB

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Lenceliv 10mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Lenceliv 10mg Capsule contains the active ingredient Lenvatinib, a tyrosine kinase inhibitor. It is indicated for progressive or advanced thyroid cancer when radioactive iodine therapy has not been effective. It is also used to treat previously untreated hepatocellular carcinoma in patients who are not eligible for surgical treatment. Lenceliv 10 Capsule 30's is used to treat specific health conditions as prescribed by your healthcare provider.

Anaplastic thyroid carcinoma is an advanced form of thyroid cancer that typically occurs in patients aged 60 years and above. It is characterised by an enlarged and hard thyroid gland and hoarseness in the voice due to nerve paralysis affecting the voice box. Hepatocellular carcinoma develops due to preexisting liver conditions such as cirrhosis or chronic hepatitis B infection.

Patients with a known allergic reaction to lenvatinib or any component of this medication should not take Lenceliv 10mg Capsule. Patients should inform their dentist or oral surgeon that they are taking Lenceliv 10mg Capsule, as it can impair wound healing and increase the risk of bleeding.

Uses

Lenceliv 10mg uses are the following conditions: Certain types of advanced thyroid cancer Advanced Liver cancer Certain types of kidney cancer Endometrial cancer

How it works

Lenceliv 10mg Capsule blocks the enzyme receptor tyrosine kinases (RTKs). RTKs develop new blood vessels that supply oxygen and nutrients to the cells and help them grow. This medicine inhibits the receptors that facilitate the growth of blood vessels in tumor cells. RTKs are present in high concentrations in cancer cells, and administration of this medicine slows down the rate of cancer cells’ growth and multiplication.

How to Use

Lenceliv 10mg Capsule is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up the second dose.

Side Effects

Like all medications, Lenceliv 10mg Capsule can cause side effects, although not everyone who takes it will experience them. Lenceliv 10 Capsule Side Effects include Serious Feeling numb or weak on 1 side of the body Severe headache Fever Confusion Difficulty speaking Vision changes Dizziness Chest pain or pressure Pain in arms, jaw, neck, back Breathing problems Severe stomach pain Blood clot formation Blood in stools or coughing blood Liver problems Pain or soreness in mouth, teeth or jaw Common High or low BP Loss of appetite Nausea, vomiting, constipation, diarrhea or indigestion Tiredness Hoarse voice Leg swelling Rashes Pain in joints or muscles Hair loss Sleeplessness Protein in urine, frequent urination Low potassium, magnesium and calcium levels in the blood Dehydration Skin problems Gall bladder inflammation Increase in the values of cholesterol, thyroid-stimulating hormone, digestive enzymes Delayed wound healing

Expert Tips

tay in close communication with your healthcare provider and report any concerns or side effects promptly. Avoid pregnancy and breastfeeding during treatment. Use effective contraception while taking Lenceliv 10mg Capsule and for at least two weeks after stopping treatment. Avoid eating grapefruits as they affect the absorption of the medication. Use sunscreen and wear protective clothing when outdoors to reduce the risk of sunburn or skin damage. Avoid strenuous activities or exercise until you understand how the medication is affecting you. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. Being informed and engaged in your treatment helps ensure the best outcomes and manage potential risks.

References

  1. Eisai Europe Limited, Electronic Medicines Compendium (EMC), [Revised on Mar 2021] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.6840.pdf
  2. Suyama and Iwase, Lenvatinib: A promising molecular targeted agent for multiple cancers, Cancer Control, 2018, 25, 1-5, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056795/pdf/10/1177 1073274818789361.pdf
  3. Q.M. Anstee, D.E.J. Jones, Liver and Biliary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
  4. M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 733-796.
  5. Eisai Inc U.S Food and Safety Drug Administration (FDA) [Last revised Aug 2018], [Accessed on 20th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/206947s007lbl.pdf

Safety Advice

Pregnancy: unsafe Lenceliv 10mg Capsule is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.

Lungs: Consult your doctor Lenceliv 10mg Capsule can cause side effects that affect the lungs, such as cough, shortness of breath, and difficulty breathing. If a person experiences any of these symptoms while taking it, they should notify their healthcare provider right away.

Breastfeeding: unsafe Breastfeeding is not recommended while taking Lenceliv 10mg Capsule, as it can potentially harm the nursing infant.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS