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Lenvabuzz 4mg Capsule

Salt Composition: LENVATINIB

₹1032.00₹1495.31

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Lenvabuzz 4mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Lenvabuzz 4mg Capsule is a tyrosine kinase inhibitor anticancer medication containing Lenvatinib. It is indicated for advanced thyroid cancer in patients who have not responded to radioactive iodine treatment. It is also used to treat hepatocellular carcinoma. In combination with other anticancer drugs, it is used to treat endometrial carcinoma, a form of advanced uterine cancer, and renal cell carcinoma.

Lenvabuzz 4mg Capsule is contraindicated in patients with hypersensitivity or allergy to Lenvatinib or its constituents. It is not recommended for use in children and adolescents below 18 years of age. Blood pressure should be maintained at optimal levels during therapy; it is not recommended for patients with grade 3 or grade 4 hypertension. Patients with grade 3 or 4 hepatotoxicity and renal failure should not use this medication. Liver and kidney function monitoring is advised during therapy.

Discontinue Lenvabuzz 4mg Capsule before any scheduled surgery after consultation with your healthcare provider. Do not administer for at least 2 weeks after major surgery or until the wound has healed properly. Inform your physician if you suspect pregnancy, are breastfeeding, or plan to become pregnant. Use during pregnancy or breastfeeding is not recommended as it may harm the fetus or infant. Effective contraception is advised during treatment and for one month after therapy completion. Consult your doctor regarding appropriate contraceptive measures. Consult your dentist before commencing Lenvabuzz 4mg Capsule, as it may decrease wound healing and increase bleeding risk. Inform your physician of all medications, including herbal and vitamin supplements, that you are taking.

Uses

Differentiated thyroid cancer Renal cell carcinoma Hepatocellular carcinoma Endometrial carcinoma

How it works

Lenvabuzz 4mg Capsule inhibits the enzyme receptor tyrosine kinase (RTK). RTKs create new blood vessels that give oxygen and nutrients to cells and promote their growth. This medication blocks the receptors that promote the formation of blood vessels in tumor cells. RTKs are found in large numbers in cancer cells, and administering this drug lowers the rate of growth and multiplication.

How to Use

Lenvabuzz 4mg Capsule is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. The dose will be decided by the physician based on your age, weight and severity of the condition you are being treated with. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Chest pain or pressure Pain in arms, jaw, neck, back Breathing problems Severe stomach pain Blood clot formation Blood in stools or coughing blood Liver problems Yellowish discoloration of skin Common High or low Blood pressure Loss of appetite Nausea, vomiting, constipation, diarrhea or indigestion Tiredness Hoarse voice Leg swelling Rashes Pain in joints or muscles Hair loss Sleeplessness Protein in urine, frequent urination Low potassium, magnesium and calcium levels in the blood Dehydration Skin problems Gallbladder inflammation Increase in the values of cholesterol, thyroid-stimulating hormone, digestive enzymes Delayed wound healing

Expert Tips

If you are receiving Lenvabuzz 4mg Capsule ensure close communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Patients should use effective contraception while taking Lenvabuzz 4mg Capsule and for at least two weeks after stopping treatment. Patients should avoid eating grapefruits as they affect the absorption of this drug. Patients are recommended to monitor their blood levels for any drop in blood cell count, elevated liver enzymes and renal toxicity. You are advised to drink plenty of fluids to stay hydrated to tackle the side effects of diarrhoea and dehydration. Patients should use sunscreen and wear protective clothing while outdoors to reduce the risk of sunburn or skin damage. You should avoid strenuous activities or exercise until you know how this medication is affecting you. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. By being informed and engaged in your treatment, you can help ensure the best possible outcomes and manage any potential risks or complications associated.

References

  1. Eisai Inc, [Revised on October 2023], [Accessed on 03-04-2024],
  2. Eisai Europe Limited, Electronic Medicines Compendium (EMC), [Revised on February 2024],[Accessed on 03-04-2024], https://www.medicines.org.uk/emc/files/pil.6840.pdf
  3. Eisai Inc, U.S Food and Safety Drug Administration (FDA) [Revised on December 2021], [Accessed on 03-04-2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/206947s021lbl.pdf
  4. Q.M. Anstee, D.E.J. Jones, Liver and Biliary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 921-988.
  5. M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 733-796.

Safety Advice

Pregnancy: unsafe It is not recommended to take Lenvabuzz 4mg Capsule during pregnancy as it has the potential to cause foetal harm. Before beginning therapy with Lenvabuzz 4mg Capsule, tell your doctor if you are pregnant, suspect you are pregnant, or planning to become pregnant.

Lungs: Consult your doctor Inform your doctor if you have liver disease because Lenvabuzz 4mg Capsule should be used cautiously with a liver condition. This medicine may also cause a rise in liver enzymes, which could indicate liver damage or inflammation. Patients using this drug must have regular blood tests to ensure that their liver function is checked.

Breastfeeding: unsafe It is not recommended to take Lenvabuzz 4mg Capsule while nursing a child because it may pass through breast milk and cause potential harm to the baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS