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Letsi 5mg Tablet

Salt Composition: LETROZOLE

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Letsi 5mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Letsi 5mg Tablet is an anti-cancer medicine that belongs to the aromatase inhibitor class. It is indicated as adjuvant therapy following primary treatment or as first-line therapy for postmenopausal women with early and advanced breast cancer whose tumours are hormone receptor-positive. Because elevated oestrogen levels are associated with breast cancer development, this medicine lowers female reproductive hormone levels by inhibiting the aromatase enzyme responsible for oestrogen synthesis. This medicine is designed to slow or arrest tumour growth and prevent spread to other body sites. Inform your physician if you have not yet attained menopause, as this medicine is ineffective in premenopausal women. Since this medicine reduces female reproductive hormone levels, it is not recommended for menstruating women due to the associated risk of fertility complications. Monitor your cholesterol levels regularly, as this medicine may elevate cholesterol. This medicine may also decrease bone mineral density. Discuss with your physician and consider regular monitoring of bone parameters. Use effective contraception during treatment and for at least 3 weeks after the final dose, as Letsi 5mg Tablet can cause when it is administered.

Uses

First and second-line treatment of postmenopausal women with hormone receptor-positive breast cancer. Supportive to standard treatment for postmenopausal women with early breast cancer. Treatment for unknown advanced breast cancer in postmenopausal women. Extended supportive therapy for postmenopausal women with early breast cancer who have already taken other anti-cancer medication.

How it works

The growth of some cancers of breasts are stimulated by estrogens. Letsi 5mg Tablet Tablet is a nonsteroidal compound that inhibits estrogen production by blocking the enzyme aromatase. This medicine reduces the tumor size and stops or slows the progression of the disease, avoiding the reoccurring of early-stage breast cancer and improving the survival rate.

How to Use

It is advised to consume Letsi 5mg Tablet exactly as your doctor prescribes. It can be consumed with or without food and should be swallowed with a glass of water. Letsi 5mg Tablet can be taken with or without food. It is better to take the tablet at a fixed time. Do not break, chew or crush the tablet.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Decreased red blood cells Decreased bone mineral density Fluid build up in lungs Common: Swelling in the face, eyes, feet, and legs Hot sweats and excessive sweating Hypercholesterolemia (high cholesterol) Constipation Heart papilation Hypertension Diarrhea Loss of appetite Nausea and Vomiting Muscle pain, bone pain, and joint stiffness Dizziness, tiredness, and sleepiness Breathing difficulty Arthralgia

Expert Tips

Notify your doctor if you have hypersensitivity because this medication is contraindicated to such a medical condition. Inform your physician if you have osteoporosis or bone fractures, and periodic monitoring of bone mineral density is required while you are on Letsi 5mg Tablet because this medicine can cause a decrease in the bone mineral density. Discuss with your doctor if you are planning for pregnancy, as this medicine shall impact the reproductive potential and might lead to fertility issues. Do not consume this medicine if you are still menstruating and have not yet gone through menopause. Report to your doctor if you are tolerant to any forms of sugar, as Letsi 5mg Tablet contains lactose ingredients. If you missed a dose, do not take a double dose for the forgotten dose. Skip the missed dose and go with regular schedule.

References

  1. Cipla (EU) Limited, Electronic Medicines Compendium (EMC), [Revised on Oct 2021], [Accessed on 22th Mar 2023], https://www.medicines.org.uk/emc/files/pil.9957.pdf
  2. Novartis Pharmaceuticals Corporation, [Revised on May 2020], [Accessed on 22th Mar 2023], https://www.novartis.us/sites/www.novartis.us/files/Femara.pdf?TB_iframe=true
  3. HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). [online] www.accessdata.fda.gov . Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020726s027lbl.pdf [Accessed on 22th Mar 2023].
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
  5. KD Tripathi, Estrogens, Progestins and Contraceptives, Essentials of Medical Pharmacology, 8th Edition, 2019, 330-353.

Safety Advice

Pregnancy: unsafe Letsi 5mg Tablet are highly unsafe during pregnancy because they may cause harm to the unborn baby. It is better to discuss with a doctor to use of an effective contraceptive method during the Letsi 5mg Tablet treatment if you still have the potential to become pregnant. It is recommended to consult your physician if you are pregnant already or suspect pregnancy.

Lungs: Consult your doctor Certain lung diseases can occur while using Letsi 5mg Tablet. consult your doctor if you have lung diseases.

Breastfeeding: unsafe It is not safe to breastfeed your baby when you are taking Letsi 5mg Tablet. It is advised to avoid breastfeeding for at least three weeks after the last dose of the medicine.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS