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Leuconamo 15mg Tablet

Salt Composition: LEUCOVORIN CALCIUM

₹409.00₹499.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Leuconamo 15mg Tablet contains the active substance Leucovorin calcium, which is chemically related to folic acid. It belongs to the class of folic acid analogues. It is used to prevent the harmful effects of methotrexate when treating certain types of cancer. It is also used to treat patients who have accidentally overdosed on methotrexate or medications belonging to a similar class. It is also used with other anticancer medications to treat colorectal cancer (cancer that begins in the colon or rectum). Other uses include treating anaemia caused by low levels of folic acid in the body.

Do not take Leuconamo 15mg Tablet if you are allergic to Leucovorin calcium, calcium folinate, or any other ingredients of this medicine, or if you have certain types of anaemia (pernicious anaemia or megaloblastic anaemia) where vitamin B12 is deficient.

Before initiating treatment, inform your physician if you have anaemia, kidney, heart, or liver problems. Inform your physician if you are using any medications for treating seizures. Notify your physician if you experience any symptoms of wheezing or trouble breathing, skin rash, itching or hives, or swelling in the lips, face, or tongue.

Uses

Methotrexate overdose and toxicity Prevent the harmful effects of methotrexate or similar medications Colorectal cancer Anemia

How it works

Leuconamo 15mg Tablet counteracts the therapeutic effects of folic acid antagonists such as methotrexate and similar medications by inhibiting the dihydrofolate reductase enzyme. It treats anaemia by supplying the folic acid needed for red blood cell formation. It treats colorectal cancer by enhancing the therapeutic effects of another anticancer medication called 5-fluorouracil.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Diarrhea Nausea Vomiting Inflamed and sore mouth Tiredness Serious Allergic reactions

Expert Tips

If you have a known intolerance to certain sugars, consult your doctor before starting this medicine. Inform your doctor if you vomit soon after receiving the injection, as it may affect treatment effectiveness. In the event of an accidental overdose, seek immediate medical attention. Do not stop taking the medication without your doctor’s recommendation, even if you feel better. Your doctor may schedule regular lab tests to track how well the medicine is working during the course of treatment.

References

  1. Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020 [cited 2023 Apr 4]. Available from: https://www.medicines.org.uk/emc/product/1572/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet]. [cited 2023 Apr 4]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020140s024lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Drug toxicity and poisoning, 12th edition, 2011, 86.
  4. KD Tripathi, Essentials of Medical Pharmacology, Haematinics and erythropoietin, 7th edition, 2013, 611.

Safety Advice

Pregnancy: Consult Your Doctor There is a limited number of studies on the safety of Leuconamo 15mg Tablet during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Lungs: Consult Your Doctor It is unknown whether Leuconamo 15mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult Your Doctor Limited information is available on Leuconamo 15mg Tablet safety during breastfeeding. Inform your physician if you are planning to breastfeed.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS