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Leucorin 15mg Tablet
Salt Composition: CALCIUM FOLINATE
- Manufacturer: SAMARTH LIFE SCIENCES PVT LTD
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 15MG
- Prescription Required
- Storage: Store leucorin 15mg tablet in a refrigerator(2°C-8°C). Keep it out of reach from children and pets.
₹406.00₹507.74
Inclusive of all taxes
Product Introduction
Leucorin 15mg Tablet is an anticancer drug belonging to the class of detoxifying agents, containing the active ingredient Calcium Leucovorin/Calcium Folinate. It is used in the treatment of megaloblastic anaemia, characterised by the presence of large, immature, and dysfunctional red blood cells (megaloblasts) in the bone marrow. It is also used to enhance the effectiveness of 5-fluorouracil in the treatment of certain cancers, by increasing the efficacy of the drug while reducing its toxicity. This drug can also be used in the treatment of overdosage of folic acid antagonists. Additionally, it helps to protect healthy cells by rescuing them from the toxic effects of the chemotherapy drug.
This drug is contraindicated in patients who have hypersensitivity reactions. This medicine may cause allergic reactions in some people. Symptoms of an allergic reaction include itching, difficulty breathing, swelling of the face or throat, and a rapid heartbeat.
Excessive doses of Leucorin 15mg Tablet must be avoided since this might impair the antitumour activity of methotrexate, especially in CNS tumours where calcium folinate accumulates after repeated courses.
There are no indications that folic acid induces harmful effects if administered during pregnancy, and it is not known whether this drug can cause foetal harm when administered to pregnant women. This drug should be used during pregnancy only when clearly needed. This medicine can be used during breastfeeding when considered necessary according to the therapeutic indications.
Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking Leucorin 15mg Tablet.
Uses
Treatment of Megaloblastic Anaemia Reduce the toxicity of methotrexate Overdose of Folic Acid Antagonists Enhance the effectiveness of 5-fluorouracil
How it works
Leucorin 15mg tablet works by enhancing the effects of folic acid in the body. It is taken up by cells through a specific transporter protein and converted into the active form of folic acid, which can be used by cells to produce DNA and form new cells. This drug is given after methotrexate to help rescue normal cells that require folate for their growth.
How to Use
Take leucorin 15mg tablet exactly as prescribed by your doctor. Do not self-administer this medicine. Do not crush or chew the tablet. Do not exceed the recommended dosage. The dose of the leucorin 15mg tablet will be decided by your doctor based on your disease condition and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Reduced number of blood cells Inflammation in the lining of mouth and intestine Severe allergic reactions Common Nausea, vomiting, severe diarrhoea Redness and swelling of palms of hands and soles of feet
Expert Tips
Special care is needed if you are elderly and you are about to receive any fluorouracil treatment and leucorin 15mg tablet at the same time in case you undergo radiotherapy or stomach trouble. Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
References
- Hospira UK Ltd, Electronic Medicines Compendium (EMC), [Revised on Feb 2021] [Accessed on 11th Apr 2023] https://www.medicines.org.uk/EMC/files/pil.1572.pdf
- Pfizer Singapore, [11th Sep 2018] [Accessed on 11th Apr 2023] http://labeling.pfizer.com/ShowLabeling.aspx?id=12130
- Package leaflet: Summary of the product characteristics for the user. www.hpra.ie. http://www.hpra.ie/img/uploaded/swedocuments/Licence_PA0749-001-001_01022022140623.pdf [Accessed on 11th Apr 2023]
- Calcium folinate sandoz - medsafe. Available at: https://www.medsafe.govt.nz/Consumers/CMI/c/calciumFolinateSandoz.pdf [Accessed on 11th Apr 2023]
Safety Advice
Pregnancy: Consult your doctor It is not known whether leucorin 15mg tablet can cause foetal harm, when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known if leucorin 15mg tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Breastfeeding: Consult your doctor It is not known if leucorin 15mg tablet passes into your breast milk or if it will affect your baby. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.