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Leuprosta Depot 11.25mg Injection

Salt Composition: LEUPROLIDE ACETATE

₹6963.00₹8703.63

Inclusive of all taxes

Leuprosta Depot 11.25mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Leuprosta Depot 11.25mg injection contains the active ingredient Leuprolide acetate, a gonadotropin-releasing hormone (GnRH) agonist. It is used to treat prostate cancer in men, hormone-responsive breast cancer, endometriosis (abnormal growth of uterine tissue outside the uterus), and uterine fibroids (benign growths of the uterus) in women. The injection is also indicated for premature puberty, characterised by early physical development in children due to hormonal imbalances.

Do not receive this injection if you are allergic to Leuprolide acetate or any ingredient in Leuprosta Depot 11.25mg, including Goserelin and Triptorelin.

Before starting treatment, inform your physician if you have liver or kidney impairment or undiagnosed abnormal uterine bleeding. Do not use this medicine if you are pregnant or planning pregnancy.

Notify your doctor about any underlying medical conditions, including diabetes, seizures, heart problems with chest pain, irregular heartbeats, depression, or increased risk of osteoporosis. During treatment, existing symptoms may temporarily worsen due to increased sex steroid levels in the body.

This medicine is not recommended for patients with abnormal vaginal bleeding. Women of childbearing age should use non-hormonal contraceptives during treatment.

Report to your doctor if: you are a man with urinary obstruction or have undergone testicle removal; your child has a progressive brain tumour; you experience spinal cord compression, urinary disorders, or haematuria (blood in urine).

Uses

Prostate cancer Hormone-responsive breast cancer in perimenopausal (around menopause) women Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus) Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)

How it works

Leuprosta Depot 11.25mg decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

How to Use

Leuprosta Depot 11.25mg injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Severe rash, itching Shortness or difficulty in breathing Cough with blood Pulmonary embolism Severe headache Common: Altered blood sugar and cholesterol levels Injection site reactions Loss of appetite Abnormal liver function Swelling in the ankle or hand Difficulty sleeping, headache Mood swings, depression Weight changes Nausea, vomiting Vaginal dryness, bleeding Loss of interest in sexual intercourse Hot flushes Bone pain, muscle weakness Breast tenderness

Expert Tips

During the treatment of breast cancer with Leuprosta Depot 11.25mg, it is recommended to undergo regular checkups every three months in combination with an aromatase inhibitor. Do not receive this injection if you experience any abnormal vaginal bleeding. Consult your doctor immediately if you or your child is suffering from a headache even after treating it with painkillers, vision problems, buzzing, or ringing in the ear. If you have diabetes, ask your doctor to monitor your glucose and blood sugar levels regularly. Before starting, inform your doctor if you are still mensurating.

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.
  3. Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023], https://www.medicines.org.uk/emc/product/4651/smpc
  4. Abbott Laboratories, US Food and Drug Administration, [Issued on Feb 2016] [ Accessed on 12th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf

Safety Advice

Pregnancy: unsafe It is unsafe to use Leuprosta Depot 11.25mg injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.

Lungs: Consult your doctor It is unknown whether Leuprosta Depot 11.25mg is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Leuprosta Depot 11.25mg injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS