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Lobetron 0.5mg Tablet

Salt Composition: LOBEGLITAZONE

₹75.00₹92.72

Inclusive of all taxes

Categories: Others

Conditions: Diabetes Mellitus

Product Introduction

Lobetron 0.5mg Tablet contains the active ingredient Lobeglitazone. It is an antidiabetic medication belonging to the thiazolidinedione class. It is indicated for the treatment of type 2 diabetes mellitus (T2DM). It may be used as monotherapy or in combination with other antidiabetic agents, including metformin or sulfonylureas. It reduces blood glucose levels and lowers HbA1C in patients with T2DM. It has demonstrated improvements in lipid profiles and hepatic function. The medication is generally well-tolerated; however, side effects including weight gain, oedema, and hepatic dysfunction may occur. Discussion with your doctor regarding risks and benefits prior to initiation is recommended. Lobetron 0.5mg Tablet is contraindicated in patients with known hypersensitivity to Lobeglitazone or other thiazolidinedione agents, and in patients with a history of hepatic failure or severe cardiac failure. Caution is advised in patients with a history of heart failure, as the medication may exacerbate this condition. Weight gain may occur; therefore, caution is warranted in patients who are overweight or obese. Oedema (fluid accumulation) may develop, so caution is advised in patients predisposed to this condition.

Uses

Treatment of type 2 diabetes

How it works

Lobetron 0.5mg Tablet is a pure PPAR-alpha agonist, meaning that it binds to and activates the peroxisome proliferator-activated receptor alpha (PPARα) in cells. PPARα is a transcription factor that plays a role in regulating metabolism, including glucose and lipid metabolism. Activating PPARα increases the number of insulin receptors on cells, making them more sensitive to insulin. This leads to a decrease in blood sugar levels.

How to Use

Read the instructions carefully before taking Lobetron 0.5mg Tablet. Take them as directed by your doctor. Take it with or without food. This will help to improve absorption. If you experience side effects, stop taking them and talk to your doctor.

Side Effects

Lobetron 0.5mg Tablet causes some side effects like all medications, although not everyone will experience them. Serious: Liver damage Heart failure Pancreatitis (pancreas inflammation) Bladder cancer Increased risk of bone fractures Severe allergic reactions Common: Shakiness Sweating Hunger Dizziness Headache Confusion Irritability Slurred speech Difficulty concentrating Loss of consciousness

Expert Tips

Before initiating treatment with Lobetron 0.5mg Tablet, disclose your medical history with the doctor, including liver disease, pancreas disease or heart problems.. Close monitoring of liver function and blood sugar monitoring is necessary during and after treatment. Additionally, potential drug interactions with other medications should be carefully evaluated, and healthcare providers should be informed about all current medications. Overdose should be avoided, and caution should be taken to reduce the risk of falls as this medication weakens the bone and raises the risk of fracture. Dose adjustments are necessary for patients with severe renal impairment or end-stage renal disease. Pregnancy and breastfeeding considerations should be discussed with a healthcare provider.

References

  1. Jaehyun Bae et al., Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus, [Published on April 2021] [ Accessed on 24th June 2023], https://ncbi.nlm.nih.gov/pmc/articles/PMC8164939/
  2. Joonsang Yoo et al., Lobeglitazone, a novel thiazolidinedione, for secondary prevention in patients with ischemic stroke: a nationwide nested case-control study, [Published on May 2023] [Accessed on 24th June 2023], https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10163714/

Safety Advice

Pregnancy: Consult your doctor There is limited information about the safety of Lobetron 0.5mg Tablet in pregnancy. If you are pregnant and considering taking them, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.

Lungs: Consult your doctor If you have a chronic lung disease and are considering taking Lobetron 0.5mg Tablet, talk to your doctor about the risks and benefits.

Breastfeeding: Consult your doctor There is limited information about the safety of Lobetron 0.5mg Tablet in breastfeeding. If you are pregnant or planning to become one, talk to your doctor about the risks and benefits. They can help you decide if they are right for you.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS