Lorbriqua 25mg Tablet

Lorbriqua 25mg tablet is a tyrosine kinase inhibitor containing lorlatinib. It is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC), the most common type of lung cancer. Metastatic non-small cell lung cancer (NSCLC) refers to lung cancer that has spread to other parts of the body, including the bones, liver, brain, or other organs. During treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent serious complications. This medicine has the potential to cause liver damage. It may also cause decreased fertility in males, which could affect your ability to father a child. Discuss any concerns about fertility with your healthcare provider. Inform your doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels, or hypertension before starting this treatment. Report to your doctor if you experience any hypersensitive reactions such as itchy skin or rashes while taking this medicine. Avoid drinking grapefruit juice while taking this drug, as it may increase the level of the drug in the blood and cause side effects. This tablet contains lactose as an inactive ingredient. In patients unable to digest lactose, a sugar found in milk and dairy products, symptoms such as bloating and abdominal pain may occur. If you have lactose intolerance, inform your doctor before starting this therapy.

Metastatic non-small cell lung cancer (NSCLC)

It works by inhibiting the tyrosine kinases, thus preventing the activation of downstream signalling pathways that are involved in cell proliferation, survival, and differentiation. This leads to the inhibition of cancer cell growth and survival.

Your doctor will decide the dose and duration of Lorbriqua 25mg tablet based on the disease condition and other factors. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Cough, chest pain, or worsening of breathing problems Feeling tired, faint, or losing consciousness Yellowing of the skin and eyes, vomiting, abdominal pain Confusion, memory loss, mood swings, difficulty speaking, seeing, or hearing things that are not real Common Increase in cholesterol levels Swelling in hand or legs Double vision difficulty seeing Pain, numbness, or unusual sensations (burning or pin and needles) in arms and legs, difficulty walking Diarrhoea, constipation Headache Weight gain Joint pain, muscle pain Rash Anaemia

Lorbriqua 25mg tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. Discuss effective nonhormonal contraceptive methods with your healthcare provider and use them during this treatment and continue for at least six months after the last dose. It is not known if this drug passes into breast milk. Hence, it is not recommended to breastfeed during this treatment. This medicine may increase your blood sugar levels. Your healthcare provider should do blood tests to check your blood sugar levels before starting and during treatment with this drug. It is important to start or change your medicine to control your blood sugar levels. Report to your doctor right away if you get new or worsening signs and symptoms of high blood sugar such as feeling thirsty, confused, and tired. This tablet might cause breathing difficulty and problems with thinking. Hence it is advisable to avoid driving or operating machines during this treatment. Before starting this treatment, inform your doctor if you are taking any prescription medicines, over-the-counter medicines, vitamins, or herbal supplements.