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Luprodex Depot 11.25mg Injection

Salt Composition: LEUPROLIDE ACETATE

₹7943.00₹9929.01

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Luprodex Depot 11.25mg injection contains the active ingredient Leuprolide acetate. It is a Gonadotropin Releasing Hormone (GnRH) agonist. This injection is indicated for prostate cancer in men, hormone-responsive breast cancer, endometriosis (tissue that normally lines the interior of the uterus growing outside of it), and uterine fibroids (noncancerous growths of the uterus) in women. It is also used to treat premature puberty, characterised by early physical development in children due to hormonal imbalances. Do not receive this injection if you are allergic to Leuprolide acetate or its ingredients, including Goserelin and Triptorelin. Before receiving this medicine, inform your physician if you have liver or kidney impairment. Inform your doctor if you have undiagnosed abnormal uterine bleeding. Do not take this treatment if you are pregnant or planning to become pregnant. During treatment, existing symptoms may worsen due to increased sex steroid levels in the body. Discuss any concerns with your physician. Report to your doctor if your child has a progressive brain tumour. Before starting treatment, notify your doctor about underlying medical conditions, such as diabetes, seizures, heart problems with chest pain, irregular heartbeats, depression, or increased risk of bone thinning (osteoporosis). This medicine is not recommended for patients with abnormal vaginal bleeding. If you are a woman of childbearing age, use non-hormonal contraceptives while taking Luprodex Depot 11.25mg injection. Report to your doctor if you are a man with urinary obstruction or have had an operation to remove your testicles. Tell your doctor if you experience pressure on the spinal cord, urinary disorders, and haematuria (blood in the urine).

Uses

Luprodex Depot 11.25Mg uses are: Prostate cancer Hormone-responsive breast cancer in perimenopausal (around menopause) women Endometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus) Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)

How it works

Luprodex Depot 11.25mg injection decreases testosterone or estrogen production, depending on the treated condition. This helps to slow the growth of cancer cells, reduce the size of uterine fibroids, and alleviate the symptoms of endometriosis and early onset of puberty.

How to Use

Luprodex Depot 11.25mg injection is usually administered in the arm, thigh or abdomen. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Side Effects

Luprodex 11.25 mg side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Severe rash, itching Shortness or difficulty of breath Cough with blood Pulmonary embolism Severe headache Common Altered blood sugar and cholesterol levels Injection site reactions Loss of appetite Abnormal liver function Swelling in the ankle or hand Difficulty sleeping, headache Mood swings, depression Weight changes Nausea, vomiting Vaginal dryness, bleeding Loss of interest in sexual intercourse Hot flushes Bone pain, muscle weakness Breast tenderness

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to Endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1122.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormones, 7th edition, 2013, 243.
  3. Takeda UK Limited, Electronic medicines compendium (emc), [ Revised on June 2022] [ Accessed on 12th April 2023], https://www.medicines.org.uk/emc/product/4651/smpc
  4. Abbott Laboratories, US Food and Drug Administration, [Issued on Feb 2016] [ Accessed on 12th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020517s036_019732s041lbl.pdf

Safety Advice

Pregnancy: unsafe It is unsafe to use Luprodex Depot 11.25mg injection because it is contraindicated in pregnant women. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.

Lungs: Consult your doctor It is unknown whether Luprodex Depot 11.25mg injection is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Luprodex Depot 11.25mg injection is contraindicated in breastfeeding women. Inform your doctor if you are breastfeeding before taking this injection.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS