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Lynparza 150mg Tablet

Salt Composition: OLAPARIB

₹235489.00₹287181.56

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Lynparza 150mg Tablet is an anticancer medication in the poly adenosine diphosphate-ribose polymerase (PARP) inhibitor class, containing olaparib as its active ingredient. It is indicated for treatment of pancreatic and prostate cancer. Cancer involves uncontrolled and abnormal cell multiplication. This medication may be administered as monotherapy or in combination with other anticancer agents. Contact your doctor immediately if you develop breathlessness, chest pain, rapid heart rate, fever, cough, or wheezing. Your healthcare provider will order blood tests before treatment initiation and monthly during treatment, as this medicine can reduce red blood cell, white blood cell, and platelet counts. Inform your healthcare provider before starting treatment if you have a history of lung, liver, heart, or kidney disease. Lynparza tablet is contraindicated in pregnancy as it may harm the developing fetus and cause miscarriage. A pregnancy test is advised before beginning this treatment in women of childbearing potential. Birth control methods should ideally be continued for a minimum of 6 months following completion of treatment. Do not breastfeed whilst receiving this treatment, as it is unknown whether Lynparza 150mg Tablet passes into breast milk.

Uses

Lynparza 150mg uses are to treat: Prostate cancer Pancreatic cancer

How it works

Lynparza 150mg Tablet works by inhibiting PARP enzymes, blocks the repair of single-stranded DNA, and ultimately hinders the growth and development of cancer cells.

How to Use

The medicine will be prescribed to you by a healthcare professional in a hospital setting. Lynparza 150mg is available as a tablet to be taken with or without food, as directed by your healthcare provider. The usual recommended dosage is 250 mg tablet once daily. Please ask your doctor to know your Lynparza 150 mg dosage. Avoid crushing, opening, or dissolving the tablet; swallow it whole with a glass of water. Take the tablet at the same time every day.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Lynparza 150mg side effects are: Common diarrhea nausea vomiting loss of appetite weakness red or sore mouth increased liver enzymes itchy or cracked skin dry mouth red or itchy eyes nail problems hair loss fever blood in the urine and a burning sensation while urinating

Expert Tips

Lynparza 150mg Tablet can reduce blood cell counts, so it is advisable to be prompt during blood check-ups. Avoid direct exposure to sunlight during this therapy, and apply sunscreen above SPF 50 before stepping out. Do not stop taking this drug without consulting your doctor. Avoid grapefruit juice during treatment with this drug since it may increase the drug concentration level in your blood.

References

  1. AstraZeneca UK Limited, Electronic medicines compendium (EMC), [Revised on Jan 2021] [ Accessed on 10 May 2023], https://www.medicines.org.uk/emc/files/pil.9204.pdf
  2. AstraZeneca Pharmaceuticals LP, US Food and Drug Administration, [Revised on Jan 2018] [Accessed on 10 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208558s001lbl.pdf
  3. Sylvia Bochum, Stephanie Berger, Uwe M Martens; Olaparib; Recent Results in Cancer Research; Published on 2018; [Accessed on 10 May 2023] https://pubmed.ncbi.nlm.nih.gov/30069770/
  4. Xiao Xia Guo et al.; The efficacy and safety of the drug Olaparib in the treatment of cancers: a meta-analysis of randomized controlled drug trials; Cancer Management and Research; Published on Aug 2018;[Accessed on 10 May 2023] https://pubmed.ncbi.nlm.nih.gov/30127642/
  5. Sebastiaan C. Goulooze et al, Olaparib, Br J Clin Pharmaco, 81:1, 171-173, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693566/pdf/BCP-81-171.pdf

Safety Advice

Pregnancy: unsafe It is unsafe to use during pregnancy whether Lynparza 150mg Tablet can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor Consult your doctor if you have any lung diseases before starting the treatment with Lynparza 150mg Tablet.

Breastfeeding: Consult your doctor Avoid breastfeeding your baby while on the treatment, as it is unknown whether Lynparza 150mg Tablet passes into the breast milk. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS