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Mabura 40mg Injection PFS
Salt Composition: ADALIMUMAB
- Manufacturer: HETERO HEALTHCARE LTD
- Pack Size: 1 PREFILLED SYRINGE(s)
- Dosage Form: INJECTION
- Strength: 40MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store in a refrigerator (2°C – 8°C). Do not freeze. Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets
₹5859.00₹23437.50
Inclusive of all taxes
Product Introduction
Mabura 40mg Injection PFS contains adalimumab, an antirheumatic agent belonging to the class of TNF (tumour necrosis factor) inhibitors. It is used alone or in combination with other medications to relieve symptoms of certain autoimmune disorders. It is indicated for the treatment of rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function), polyarticular juvenile idiopathic arthritis (a condition affecting children in which the body attacks its own joints, causing pain, swelling, loss of function, and delays in growth and development), enthesitis-related arthritis, ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain and joint damage), axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin), plaque psoriasis, hidradenitis suppurativa (a skin disease that causes pimple-like bumps in the armpits, groin, and anal area), Crohn's disease, ulcerative colitis (a condition which causes swelling and sores in the lining of the colon and rectum), and non-infectious uveitis (swelling and inflammation of different areas of the eye).
Do not use Mabura 40mg Injection PFS if you are allergic to adalimumab or any of the other ingredients in this medicine. Do not use this medicine if you have active tuberculosis or other severe infections. Do not use this medicine if you have moderate or severe heart failure. Inform your doctor if you have any active infection before starting treatment. Tell your doctor if you have lung problems, heart disease, liver or kidney disorders before initiating treatment. If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice about taking this medicine.
Uses
Rheumatoid arthritis Polyarticular juvenile idiopathic arthritis Enthesitis-related arthritis Ankylosing spondylitis Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis Psoriatic arthritis Plaque psoriasis Hidradenitis suppurativa Crohn’s disease Ulcerative colitis Non-infectious uveitis
How it works
The active ingredient in this medicine is a human monoclonal antibody. Monoclonal antibodies are proteins that attach to a specific target. The target of Mabura 40mg Injection PFS is a protein called tumor necrosis factor (TNFα), which is involved in the immune (defense) system and at increased levels in the inflammatory diseases. By attaching to TNFα, Humira decreases inflammation in these diseases.
How to Use
Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severity and other factors. Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained. Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severeity and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Injection site reactions Rash Headache Sinusitis Upper respiratory infections Fever Serious Heart problems Abnormal heart beat Severe skin reactions GI bleeding Abnormal blood count values Liver injury Bone problems Infections Severe respiratory problems
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1018.
- KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 213.
- AbbVie Ltd, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on July 2023], https://www.medicines.org.uk/emc/files/pil.2150.pdf
- AbbVie Inc, US Food and Drug Administration, [ Revised on Feb 2021] [ Accessed on July 2023], https://www.rxabbvie.com/pdf/humira.pdf
Safety Advice
Pregnancy: Consult Your Doctor Do not take Mabura 40mg Injection PFS during pregnancy unless your doctor says. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.
Lungs: Consult Your Doctor Mabura 40mg Injection PFS should be taken cautiously in patients with lung problems. Inform your physician if you have any lung diseases before initiating the treatment.
Breastfeeding: Consult Your Doctor Mabura 40mg Injection PFS can be used during breastfeeding. However, inform your physician if you are breastfeeding
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.