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Mabvinra 40mg Injection

Salt Composition: ADALIMUMAB

₹6094.00₹9374.06

Inclusive of all taxes

Categories: Rheumatology

Conditions: Osteoporosis

Product Introduction

Mabvinra 40mg Injection is a TNF (tumour necrosis factor) inhibitor belonging to the class of antirheumatic agents. The active compound is Adalimumab. It is used to treat symptoms of several autoimmune diseases, either alone or in combination with other medications.

Do not take Adalimumab if you are allergic to the active compound or any other ingredients in this medicine. Mabvinra 40mg Injection is not advised if you have a severe infection such as tuberculosis, sepsis, or other infections. It should not be used if you have a compromised immune system. Avoid this medication if you suffer from moderate or severe heart failure. If you have an active infection, inform your doctor before beginning treatment. Before starting treatment, inform your doctor if you have any heart, liver, or renal issues.

Children aged six years or below should visit your doctor before using Mabvinra 40mg Injection. Patients aged above 65 years are more susceptible to infections whilst using Mabvinra 40mg Injection; it is important to monitor them closely for any side effects they develop. It is advised that your child receive an up to date vaccination schedule to reduce the chance of developing infections.

The use of Mabvinra 40mg Injection during pregnancy and breastfeeding will be determined by your doctor only if absolutely necessary, as it may cause infections in the child. It is recommended to use effective contraceptive methods during therapy and for 5 months after completion. Inform your doctor if you are pregnant or planning to become pregnant to discuss effective contraceptive methods.

It is necessary to inform your physician about all medicines, over the counter drugs, vitamins, and herbal supplements you are taking before starting therapy. Patients taking Mabvinra 40mg Injection should be closely monitored by their healthcare provider for any signs of side effects.

Uses

Rheumatoid arthritis Polyarticular juvenile idiopathic arthritis Enthesitis-related arthritis Ankylosing spondylitis Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis Psoriatic arthritis Plaque psoriasis Hidradenitis suppurativa Crohn’s disease Ulcerative colitis Non-infectious uveitis

How it works

Mabvinra 40mg Injection restricts TNF-alpha's ability to connect with its receptors, which in turn prevents TNF-alpha from mediating downstream signaling pathways. The inflammatory response, which includes immune cell activation, inflammatory cytokine generation, and recruitment of inflammatory cells to inflammatory areas, is largely regulated by these signaling pathways. By restricting the signaling pathway it decreases inflammation in various autoimmune diseases.

How to Use

Mabvinra 40mg Injection is administered by injection under the skin (subcutaneously). The dosage and frequency of Mabvinra 40mg Injection will depend on various factors, including the patient's age, weight, overall health, and the type and stage of disease being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained. If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It's important not to take a double dose of Mabvinra 40mg Injection to make up for a missed dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common: Injection site reactions Rash Headache Sinusitis Upper respiratory infections Fever Serious Heart problems Abnormal heart beat Severe skin reactions GI bleeding Abnormal blood count values Liver injury Bone problems Infections Severe respiratory problems

Expert Tips

If you have prescribed Mabvinra 40mg Injection or any other medication, it is important to follow the instructions provided by your healthcare provider and to report any side effects or concerns promptly. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Mabvinra 40mg Injection. It is recommended to monitor your blood counts at regular intervals. Include anti-inflammatory foods in your diet, such as olive oil, nuts, seeds, fruits, vegetables, and fatty fish. Include foods like avocados, almonds, seeds, and olive oil in your diet as sources of healthful fats. These fats can improve general health by lowering inflammation. To stay hydrated, sip lots of water throughout the day. Consult your physician before getting any vaccinations because certain of them can make you sick and should not be administered while you are on this medication. If you currently have or have ever had hepatitis B, let your doctor know as this medication may make the illness more likely to recur. One may receive instruction on administering medication at home. Before administering an injection to yourself, be sure you understand all the instructions. Every time you give yourself a shot, use a new part of your body. Make sure you rotate body parts by keeping track of where you administer each shot. Injecting into areas of skin that are hard, tender, bruised, or red is not advised. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.

References

  1. Amgen Limited, Electronics Medicines Compendium(emc), [ Revised on February 2023] [ Accessed on 27-03-2024], https://www.medicines.org.uk/emc/files/pil.9546.pdf
  2. AbbVie Inc, United States Food and Drug Administration (US FDA), [ Revised on November 2023] [Accessed on 27-03-2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/125057s423lbl.pdf
  3. AbbVie Inc, [Revised on February 2024], [Accessed on 27-03-2024], https://www.rxabbvie.com/pdf/humira.pdf

Safety Advice

Pregnancy: Consult your doctor Mabvinra 40mg Injection should not be taken while pregnant unless prescribed by a physician. Your physician will prescribe it only if necessary on an individual case to case basis. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.

Lungs: Consult your doctor Mabvinra 40mg Injection should be used with caution in individuals who have respiratory issues. Let your doctor know if you have any lung conditions before starting any treatment.

Breastfeeding: Consult your doctor The mother's clinical requirement for Mabvinra 40mg Injection and any potential negative effects on the breastfed infant are compared and your physician will prescribe only if the benefits outweigh the risks. Your physician will prescribe it only if necessary on an individual case to case basis.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS