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MBvorin 50mg Injection
Salt Composition: LEUCOVORIN CALCIUM
- Manufacturer: MEDICAMEN BIOTECH LTD
- Pack Size: 1 VIAL(s) OF 5ML
- Dosage Form: INJECTION
- Strength: 50MG
- Prescription Required
- Storage: Store MBvorin 50mg Injection in a refrigerator at 2° to 8°C Keep the injection away from the reach of children and pets. If you forgot your dosing schedule, inform your healthcare professional immediately and reschedule the dosing
₹216.00₹360.00
Inclusive of all taxes
Product Introduction
MBvorin 50mg Injection contains the active substance Leucovorin calcium, which is chemically related to a vitamin called folic acid. It belongs to the class of folic acid analogues. It is used to prevent the harmful effects of methotrexate medicine when treating certain types of cancer. It is also used to treat patients who have accidentally overdosed on methotrexate medicine or medications that belong to a similar class. It is also used with other anticancer medications to treat colorectal cancer (cancer that begins in the colon or rectum). Other uses include treating anaemia caused by low levels of folic acid in the body. Do not take MBvorin 50mg Injection if you are allergic to Leucovorin calcium, calcium folinate, or any other ingredients of this medicine, or if you have certain types of anaemia (pernicious anaemia or megaloblastic anaemia) where vitamin B12 is deficient. Before initiating treatment, inform your doctor if you have anaemia, kidney, heart, or liver problems. Inform your doctor if you are using any medications for treating seizures. Notify your doctor if you experience any symptoms of wheezing or trouble breathing, skin rash, itching or hives, or swelling in the lips, face, or tongue.
Uses
Methotrexate overdose and toxicity Prevent the harmful effects of methotrexate or similar medications Colorectal cancer Anemia
How it works
MBvorin 50mg Injection counteracts the therapeutic effects of folic acid antagonists such as methotrexate and similar medications by inhibiting the dihydrofolate reductase enzyme. It treats anaemia by supplying the folic acid needed for red blood cell formation. It treats colorectal cancer by enhancing the therapeutic effects of another anticancer medication called 5-fluorouracil.
How to Use
A trained physician or nurse in cancer chemotherapy will administer the drug to you. Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. The medicine is administered either intravenously (into your vein) or intramuscularly (into your muscle) based on your disease condition.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Diarrhea Nausea Vomiting Inflamed and sore mouth Tiredness Serious Allergic reactions
Expert Tips
If you have a known intolerance to certain sugars, consult your doctor before starting this medicine. Inform your doctor if you vomit soon after receiving the injection, as it may affect treatment effectiveness. In the event of an accidental overdose, seek immediate medical attention. Do not stop taking the medication without your doctor’s recommendation, even if you feel better. Your doctor may schedule regular lab tests to track how well the medicine is working during the course of treatment.
References
- Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020 [cited 2023 Apr 4]. Available from: https://www.medicines.org.uk/emc/product/1572/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet]. [cited 2023 Apr 4]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020140s024lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Drug toxicity and poisoning, 12th edition, 2011, 86.
- KD Tripathi, Essentials of Medical Pharmacology, Haematinics and erythropoietin, 7th edition, 2013, 611.
Safety Advice
Pregnancy: Consult Your Doctor There is a limited number of studies on the safety of MBvorin 50mg Injection during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Lungs: Consult Your Doctor It is unknown whether MBvorin 50mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: Consult Your Doctor Limited information is available on MBvorin 50mg Injection safety during breastfeeding. Inform your physician if you are planning to breastfeed.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.