Home › Products › Oncology › Megacet 160mg Tablet

Megacet 160mg Tablet

Salt Composition: MEGESTROL

₹587.00₹649.59

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Megacet 160mg Tablet contains Megestrol, a synthetic progestin that belongs to the class of hormonal antineoplastic medicines. It is primarily used to treat hormone-dependent cancers, such as breast cancer and endometrial cancer, by regulating hormone activity and slowing the growth and spread of cancer cells.

In addition to its cancer-related uses, Megacet 160mg Tablet is commonly prescribed to improve loss of appetite (anorexia) and unexplained weight loss in patients with advanced cancer or HIV/AIDS. By increasing appetite, it helps promote healthy weight gain, improve nutritional intake, and enhance overall well-being.

Before taking Megacet 160mg Tablet, patients should consult their doctor and disclose their complete medical history, current medications, and any known allergies. This helps ensure the medicine is used safely and effectively. Megestrol is not recommended during pregnancy because it may cause harm to the unborn baby. It should also be used with caution in individuals who have a history of blood clots, stroke, or other thromboembolic conditions.

For the best therapeutic results, Megacet 160mg Tablet should be taken exactly as prescribed by a healthcare professional. Regular medical check-ups and monitoring are important to evaluate treatment response, manage potential side effects, and ensure the safe and effective use of the medication.

Uses

Treatment of hormone-dependent cancer (endometrial cancer, breast cancer) Treatment of anorexia, cachexia or unexplained weight loss

How it works

Megacet 160mg Tablet, containing megestrol, is a synthetic progestin used primarily for managing hormone-sensitive cancers like breast and endometrial cancer, where it alters hormonal pathways to slow cancer cell growth. It is also prescribed to treat cancer-related cachexia and anorexia, helping improve appetite and promote weight gain in patients with severe weight loss due to advanced cancer or HIV/AIDS. Additionally, it exhibits anti-inflammatory and immune-modulating properties, making it beneficial in certain chronic conditions. However, caution is required in individuals with diabetes, thromboembolic disorders, or adrenal insufficiency, as it can affect metabolic and hormonal balance, necessitating close medical supervision.

How to Use

Megacet 160mg Tablet should be taken exactly as prescribed by a healthcare professional. It is usually taken orally with or without food, but taking it at the same time each day helps maintain consistent blood levels. The tablet should be swallowed whole with a glass of water and should not be crushed, broken, or chewed. The dosage and duration depend on the patient's medical condition and response to treatment. It is important not to stop or adjust the dose without consulting a doctor. If a dose is missed, it should be taken as soon as remembered, but if it is almost time for the next dose, the missed dose should be skipped to avoid double dosing. Always follow your doctor’s instructions and read the patient information leaflet for any specific guidelines related to your condition.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Swelling of the face, lips, tongue Skin rash Breathing difficulty Blood clots in the lungs Heart problems Common: Weight gain and increased appetite Hot flushes High BP High blood sugar levels Rounded face Constipation Swelling of vein Mood changes Hair loss Diarrhea Tiredness and weakness Impotence Passing wind Frequent urination Nausea, vomiting Fluid accumulation Pain

Expert Tips

Inform the doctor if the patient has any history of kidney, liver, allergic reactions before starting this medication. Kidneys,liver, blood pressure and blood glucose levels should be monitored while taking this medication and avoid taking this medication while planning for pregnancy or during pregnancy as it causes harmful effects on developing babies. This medication should not be stopped without proper advice from the doctor because it can worsen the situation. Inform the doctor immediately if there are any signs of swelling and pain in the limbs, shortness of breath, chest pain, severe headache, or changes in vision.

References

  1. Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
  2. alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
  3. Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
  4. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.

Safety Advice

Pregnancy: unsafe Megacet 160mg Tablet is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.

Lungs: Consult your doctor Inform your physician before starting Megacet 160mg Tablet if you have lung disease.

Breastfeeding: Consult your doctor Consult your physician before taking Megacet 160mg Tablet if you are a breastfeeding mother.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS