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Megapharm 160mg Tablet

Salt Composition: MEGESTROL

₹459.00₹1020.94

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Megapharm 160mg Tablet contains megestrol, a progestogen used to treat hormone-dependent breast cancer. It is a synthetic form of the naturally occurring progesterone hormone. The tablet is also indicated for treatment of unexplained weight loss, cachexia and anorexia in patients with cancer and compromised immune function. Progestogens are employed in patients whose disease has advanced despite conventional anti-estrogen therapy. Your physician will evaluate estrogen receptor (ER) status to confirm that your breast cancer is dependent on oestrogen receptor expression.

Uses

Treatment of hormone-dependent cancer (endometrial cancer, breast cancer) Treatment of anorexia, cachexia or unexplained weight loss

How it works

Megapharm 160mg Tablet exhibits anticancer properties by interacting with steroidal receptors. It suppresses steroid production by the adrenal glands and androgen secretion by the ovaries in postmenopausal women. It also prevents the breakdown of cytokines and stimulates appetite in chronic disease-induced anorexia and cachexia.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Swelling of the face, lips, tongue Skin rash Breathing difficulty Blood clot in the lungs Heart problems Common: Weight gain and increased appetite Hot flushes High BP High blood sugar levels Rounded face Constipation Swelling of vein Mood changes Hair loss Diarrhea Tiredness and weakness Impotence Passing wind Frequent urination Nausea, vomiting Fluid accumulation Pain

Expert Tips

Inform your doctor if you have a history of kidney problems, liver issues, or allergies before starting this medication. Your kidney function, liver function, blood pressure, and blood sugar levels should be regularly monitored during treatment. Avoid using this medicine during pregnancy or while planning for pregnancy, as it may harm the developing baby. Do not stop taking this medication without your doctor’s advice, as sudden discontinuation may worsen your condition. Seek medical help immediately if you notice swelling or pain in the limbs, chest pain, shortness of breath, severe headache, or vision changes.

References

  1. Bausch and Lomb UK Ltd., Electronic Medicines Compendium (EMC), [Revised on Sep 2020] [Accessed on 17th Jul 2021], https://www.medicines.org.uk/emc/files/pil.11135.pdf
  2. alniche Life Sciences Pvt Ltd., [Revised on 2021] [Accessed on 19th Jul 2021], https://www.alniche.com/product/megahenz/
  3. Bines et al., Activity of megestrol acetate in postmenopausal women with advanced breast cancer after nonsteroidal aromatase inhibitor failure: a phase II trial, Annals of Oncology, 2014, 25(4), 831-836, https://www.annalsofoncology.org/action/showPdf?pii=S0923-7534%2819%2936501-9
  4. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 259-282.

Safety Advice

Pregnancy: Unsafe This medicine is unsafe to consume during pregnancy. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.

Lungs: Consult Your Doctor Inform your physician if you have any lung diseases before taking Megapharm 160mg Tablet.

Breastfeeding: Consult Your Doctor Consult your physician before taking this tablet if you are a breastfeeding mother.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS