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Megval 50mg Injection

Salt Composition: MELPHALAN

₹2077.00₹2597.00

Inclusive of all taxes

Megval 50mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Megval 50mg injection contains melphalan as the active constituent. It is an anticancer agent belonging to the class of alkylating agents. It is indicated for the treatment of multiple myeloma, a cancer of the bone marrow. It is also used in advanced ovarian cancer. Additional indications include childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer), and soft tissue sarcoma (cancer of muscle, fat, fibrous tissue, blood vessels, or other supporting tissues of the body). The medicine works by reducing the number of abnormal cells produced by your body.

Do not take Megval 50mg injection if you are allergic to melphalan or any other ingredients in the formulation. Inform your physician if you have recently undergone radiotherapy or cancer chemotherapy, or if you have a kidney problem. Do not take this medicine if you are pregnant or planning pregnancy. Inform your doctor if you have received any vaccination recently or are planning to undergo vaccination. Report to your physician immediately if you experience a rash, lumps or hives on the skin, swollen face, eyelids or lips, sudden wheeziness, or chest tightness following administration of the injection.

Uses

Multiple myeloma Advanced ovarian cancer Childhood neuroblastoma Malignant melanoma Soft tissue sarcoma

How it works

Megval 50mg injection is an alkylating agent. It exerts its cytotoxic action primarily due to the cross-linking of strands of DNA and RNA, as well as the inhibition of protein synthesis. It works by stopping or slowing the growth of cancer cells in your body.

How to Use

Megval 50mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy. This injection can be given as an infusion into your vein, or it will be given as a perfusion to a particular part of your body through an artery. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Decreased blood cell count Nausea, vomiting, diarrhea Mouth ulcers Hair loss Serious Cardiac arrest Liver inflammation Hypersensitivity skin reactions Acute renal failure Lung inflammation

Expert Tips

This medicine may cause changes in your blood levels. Your doctor may advise you to take certain blood tests during the treatment to monitor any unwanted side effects. Do not take an extra dose to make up for a missed dose. This medicine could cause infertility. Talk with your doctor before using this medicine if you are planning for pregnancy. This medicine may you to bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.

References

  1. Melphalan 50 mg Powder and Solvent for Solution for Injection/Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [revised on 2020] [cited 2023 Apr 7]. Available from: https://www.medicines.org.uk/emc/product/927/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION - Melphalan injection [revised on 2017] [cited 2023 Apr 7]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207155s001lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.

Safety Advice

Pregnancy: unsafe Do not take Megval 50mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

Lungs: Consult your doctor It is unknown whether Megval 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Megval 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS