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Meqsel 2mg Tablet

Salt Composition: TRAMETINIB

₹172969.00₹181875.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Meqsel 2mg Tablet contains trametinib as its active ingredient. It is a prescription medication indicated for the treatment of certain cancers. Cancer is a disorder characterised by uncontrolled and abnormal multiplication of cells. This medication inhibits cell growth and division in cancer cells and is used in the treatment of advanced melanoma. It is typically administered with another drug (dabrafenib) to enhance treatment outcomes. This medication is used to treat melanoma, a type of skin cancer that cannot be surgically removed or has spread to other parts of the body. It also prevents melanoma recurrence following surgical removal. It is also used to treat non-small cell lung cancer (NSCLC), a form of lung cancer. Like all medications, it may cause side effects. The most common side effects include rash, diarrhoea, nausea, vomiting, fatigue, and peripheral oedema (swelling of the hands and feet). Inform your doctor if you have liver disorders, kidney disorders, breathing difficulties, heart disease, or eye problems before taking Meqsel 2mg Tablet. It is not recommended for children and adolescents under 18 years of age and for those who are allergic to trametinib or any of its components. The recommended dose is one tablet daily, taken orally with or without food.

Uses

Metastatic melanoma Use in combination with dabrafenib for improved treatment outcomes of melanoma Used in treatment of non-small cell lung carcinoma Used in treating metastatic anaplastic thyroid cancer Metastatic solid tumours

How it works

Meqsel 2mg Tablet works by blocking the activity of a protein called Mitogen-activated protein kinase kinase (MEK), which is part of the Mitogen-activated protein kinase (MAPK) signaling pathway. This pathway is critical in regulating cell growth, division, and survival. It helps slow or stop cancer cell growth and spread by blocking MEK.

How to Use

Meqsel 2mg Tablet is usually taken orally as a tablet. It can be taken either with or can also be taken without food. Your specific condition, such as medical conditions, age, weight, and overall health, will decide the dosage and duration of treatment. It is essential to follow the instructions provided by the healthcare provider or pharmacist when taking. Generally, the tablet should be swallowed whole with a full glass of water. You should not crush, chew, or break the tablet. If a dose is missed, it is important to take it as soon as possible unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. It would help if you did not take two drug doses together to compensate for a missed dose.

Side Effects

Side effects are unwanted symptoms that occur due to medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Heart failure Irregular heartbeat Shortness of breath Liver injury or hepatitis Retinal detachment Gastrointestinal perforation (a hole or tear in the stomach or intestine) Stevens-Johnson syndrome (a severe skin reaction) Common: Nausea Diarrhoea Fatigue Skin rash Acne Dry skin Headache Fever Swelling in the hands or feet High blood pressure Eye problems, such as blurred vision or sensitivity to light

Expert Tips

If you have been prescribed Meqsel 2mg Tablet or any other medication, it is important to follow the instructions provided by your healthcare provider and promptly report any side effects or concerns. It can cause serious side effects, so it is important to monitor your symptoms and seek medical attention if you experience any concerning changes in your health. It is also important to avoid alcohol and to follow any safety recommendations provided by your healthcare provider. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. Patients with liver or kidney disease should use it cautiously. During pregnancy or breastfeeding it is not recommended. Discussing all medical conditions and medications with a healthcare provider before starting treatment is important. With proper monitoring and management, this medication can be an effective treatment option for certain types of cancer.

References

  1. Novartis Europharm Limited, Electronic medicines compendium (emc),[ Revised on Nov 2022] [Accessed on 28th March 2023], https://www.medicines.org.uk/emc/product/5072/smpc
  2. Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [Revised on April 2018] [ Accessed on 28th March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/204114s007lbl.pdf
  3. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1625-1626
  4. Katzung and Trevor, Basic and Clinical Pharmacology, 14th Edition, 2018, 579

Safety Advice

Pregnancy: unsafe Meqsel 2mg Tablet is unsafe for pregnant women as it may cause foetal harm. It is not recommended to take it during pregnancy.

Lungs: Consult your doctor Meqsel 2mg Tablet has been associated with some lung-related side effects, although these are relatively uncommon. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Meqsel 2mg Tablet is unsafe during breastfeeding. Because of the potential risk to the infant, breastfeeding is not recommended during treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS