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Metbleo 15IU Injection

Salt Composition: BLEOMYCIN

₹520.00₹650.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Metbleo 15IU Injection contains the active ingredient Bleomycin. It is an antineoplastic antibiotic used in cancer treatment to slow or stop the growth of cancer cells. It is indicated for lymph node cancers (Hodgkin's and non-Hodgkin's lymphoma), head and neck cancer, and cancer in external genitalia. It may be used alone or in combination with radiotherapy and chemotherapy treatment. This injection is also used to prevent and treat fluid accumulation in the lungs due to cancer. It works by interfering with the production of DNA and RNA in cancer cells, causing breaks in DNA strands and preventing cancer cells from dividing and growing. Metbleo 15IU injection can cause side effects, including lung problems, skin reactions, fever, and nausea. In some cases, it can also affect the kidneys, liver, and heart. Patients receiving this injection require close monitoring for these side effects. It is typically administered through injection or infusion, either alone or in combination with other chemotherapy drugs. The dosage and frequency of treatment depend on several factors, including the type and stage of cancer, the patient's age and overall health, and the specific treatment plan developed by the oncologist.

Uses

Hodgkin's lymphoma Non-Hodgkin's lymphoma Testicular cancer Some types of lung cancer

How it works

The therapeutic effect of Metbleo 15IU Injection is inhibiting cancer cell growth and proliferation. By interfering with DNA replication and transcription, it can slow or stop the growth of cancer cells, leading to their destruction. This effect is particularly important in the treatment of Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, and some types of lung cancer, where rapid cell growth and division are characteristic features of the disease. Overall, this medication can help to shrink tumours and improve symptoms in cancer patients.

How to Use

Metbleo 15IU Injection is administered through injection by a healthcare provider in a hospital or clinical setting. The dosage and frequency of administration will vary depending on the type of cancer being treated, the patient's age and weight, and other factors. It should not be taken orally, as it is not absorbed well through the gastrointestinal tract and may cause serious side effects if ingested. During treatment, patients should follow their healthcare provider's instructions closely and attend all scheduled appointments for monitoring of their condition and response to treatment. If a dose of the drug is missed, patients should contact their healthcare provider immediately for instructions on when to take the next dose. It is important not to double the dose to make up for a missed one.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Fever Chills Fatigue Loss of appetite Nausea and vomiting Mouth sores Skin rash or itching Hair loss Cough or shortness of breath, Low blood cell counts, Serious Interstitial pneumonitis (inflammation of lung linings) Pulmonary fibrosis Liver toxicity Kidney toxicity Allergic reactions Increased risk of infections

Expert Tips

Following your healthcare provider's instructions is important if you have been prescribed Bleocel 15IU Injection. Take the medication as prescribed and promptly report any side effects or symptoms to your healthcare provider. Take steps to maintain your overall health, such as eating a balanced diet, getting enough rest, and exercising regularly, as these can help support your body's ability to tolerate medication and recover from treatment. To ensure the safest and most effective treatment, following all safety advisories related to this injection is important. Women of childbearing age should use effective birth control during treatment and afterward, as this medication can harm a developing fetus. Patients with liver or kidney disease may also require lower doses or more frequent monitoring during treatment. Patients should avoid alcohol while taking it, as it can increase the risk of liver toxicity and other side effects. Communicate openly with your healthcare provider about any concerns or questions about your treatment. If you experience serious side effects or medical emergencies, seek medical attention immediately. With careful monitoring and communication, your healthcare provider can help you navigate any challenges or concerns during treatment.

References

  1. Nippon Kayaku Co., Ltd., US Food and Drug Administration, [Revised on April 2010], [Accessed on 1st Apr 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/050443s036lbl.pdf
  2. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
  3. Accord Healthcare Limited, Electronic Medicines Compendium(EMC), [Revised on Mar 2018] [Accessed on 1st Apr 2023], https://www.medicines.org.uk/emc/files/pil.9333.pdf
  4. DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology, 11th edition. Lippincott Williams & Wilkins, 2019, 573-582.
  5. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 13th Edition. McGraw Hill Education, 2017, 1317-1322

Safety Advice

Pregnancy: unsafe Metbleo 15IU Injection is not safe for pregnant women as it may cause foetal harm. So it is not recommended to take this during pregnancy.

Lungs: unsafe Metbleo 15IU Injection should be used with caution in patients with pre-existing lung disease or a history of lung surgery. It can cause lung toxicity, including interstitial pneumonitis and pulmonary fibrosis, which can be life-threatening. Patients with pre-existing lung disease, such as chronic obstructive pulmonary disease (COPD) or asthma, may be at higher risk of developing lung toxicity. Patients taking it should be closely monitored for signs of lung toxicity, including shortness of breath, cough, fever, and chest pain.

Breastfeeding: Consult your doctor It is not known weather it is excreted in human milk or not. So if you are nursing an infant then it is better to consult a doctor before taking this medication.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS