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Methnilon 500mg Injection

Salt Composition: METHYLPREDNISOLONE

₹240.00₹342.19

Inclusive of all taxes

Categories: Rheumatology

Conditions: Arthritis

Product Introduction

Methnilon 500mg injection is an anti-inflammatory drug belonging to the class of glucocorticoids, containing the active ingredient methylprednisolone. It is used to treat inflammatory or allergic conditions affecting the brain (caused by tumour or meningitis), lungs (caused by asthma, hypersensitivity, tuberculosis, or aspiration of vomit or stomach contents), gut, and bowel (Crohn's disease and ulcerative colitis). It treats rheumatic, skin, eye, and endocrine disorders. It is also used for palliative management of cancers (leukaemia and lymphoma) and reduction of pain after surgery. In higher doses, it is used to treat flare-ups of symptoms of multiple sclerosis. This injection should not be used if you have a fungal infection, cerebral oedema due to malaria, traumatic brain injury, or if you have recently been vaccinated or are about to receive any vaccination. Common side effects likely to occur with this medicine include headache, vision problems, poor wound healing, and bone weakness. Serious side effects also include blood clots in leg veins and lungs, and bleeding ulcers. Inform your healthcare provider if these side effects concern you or persist for longer than usual. This drug can increase the risk of certain eye problems, such as posterior subcapsular cataracts and glaucoma. These conditions can lead to vision loss if not treated appropriately. Additionally, corticosteroids can weaken the immune system, making patients more susceptible to secondary ocular infections caused by fungi or viruses. Therefore, it is important to use corticosteroids at the lowest effective dose for the shortest possible duration to minimise the risk of these side effects. If you experience any changes in your vision or eye discomfort while taking Methnilon 500mg injection or any other corticosteroid, inform your doctor promptly. Your healthcare provider will monitor your blood pressure, electrolyte levels, and kidney function closely while you are taking corticosteroids to prevent side effects. Additionally, all corticosteroids can increase calcium excretion, which can lead to osteoporosis and increased fracture risk with prolonged use. Your doctor will prescribe calcium and vitamin D supplementation to help maintain bone health while taking corticosteroids. Tell your physician about all medications you have been taking recently, including herbal medicines and supplements, before taking this injection.

Uses

Treatment of allergic conditions Rheumatic, blood, skin, eye, and endocrine disorders Leukemia and lymphomas (palliative management) Pain related to surgery (organ transplants) Multiple sclerosis Ulcerative colitis

How it works

It works by binding to glucocorticoid receptors and inhibits the production of substances (such as prostaglandins) that lead to inflammation and allergies.

How to Use

Methnilon 500mg injection will be administered to you by a healthcare professional in a hospital setting. This injection will be given intramuscularly or intravenously into a vein in your arm. Do not self-administer this medicine. It is available in two strengths 40 mg/mL and 80 mg/mL. The dose of the injection will be decided by your doctor based on your disease condition and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Allergic reactions (wheezing, swelling of face, difficulty breathing) Stomach pain spreading to your back, accompanied by vomiting and loss of consciousness Bleeding ulcers Infections Blood clots in the lung (chest pain, coughing up blood, breathlessness) Raised pressure within the skull (lack of energy, drowsiness) Blood clots in the leg vein Common High blood pressure, headache Swelling Ulcers Vision problems Poor wound healing Round or moon-shaped face Slow growth in infants, children, and adolescents Muscle and bone weakness Feeling depressed or high, difficulty in thinking, memory loss Acne, bruising Thinning of skin

Expert Tips

Methnilon 500mg injection can cause harm to a developing fetus or nursing baby, so it is important to notify your physician if you are pregnant, breastfeeding, or planning to have a baby. Grapefruit juice and grapefruit should be avoided by individuals taking this drug. This medicine can cause several side effects related to electrolyte and fluid balance. When given in large doses, these medications can increase blood pressure, cause salt and water retention, and increase the excretion of potassium. These effects are less likely to occur with prolonged use or high doses. To prevent these side effects, dietary salt restriction and potassium supplementation may be necessary.

References

  1. Pfizer Limited, Electronic medicines compendium (EMC), [ Revised on April 2021] [ Accessed on 7th July 2021], https://www.medicines.org.uk/emc/files/pil.1550.pdf
  2. Pfizer, US Food and Drug Administration, [ Revised on Oct 2011] [ Accessed on 7th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/011856s103s104lbl.pdf
  3. Medrol, Food and Drug Administration, (Accessed on March 20, 2023), https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/011153s075lbl.pdf
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, ACTH, adrenal steroids, and pharmacology of the adrenal cortex, 12th edition, 2011, 1231.
  5. KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 2013, 288.

Safety Advice

Pregnancy: unsafe Methnilon 500mg injection is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment. A dose adjustment is suggested.

Lungs: Consult your doctor It is not known whether Methnilon 500mg injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients administered with a Methnilon 500mg injection because it may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS