Mexate 5mg Tablet

Mexate 5mg tablet contains methotrexate, an anti-metabolite and immunosuppressant drug. It is indicated for treatment of certain cancers in adults, including acute lymphocytic leukaemia (ALL), meningeal leukaemia, non-Hodgkin's lymphoma, soft tissue and bone sarcoma, cutaneous T-cell lymphoma, breast cancer, and head and neck cancer. It is also used to treat severe psoriasis in adults (a skin condition in which red, scaly patches develop on areas of the body) and rheumatoid arthritis in adults (a disease affecting the joints).

Do not use Mexate 5mg tablet if you are allergic to methotrexate or any other ingredient in this medicine. Do not take this medicine if you have kidney or liver problems, blood disorders, a weakened immune system, or if you are pregnant or breastfeeding. Inform your physician immediately if you experience spitting and coughing up blood, general muscle weakness, vision disturbance, or changes in thinking, memory, and orientation.

This medicine may impair fertility. Avoid pregnancy during treatment and for six months after the last dose. Inform your doctor if you have a stomach ulcer, active infection, or mild kidney problems, and about any recent vaccinations before starting treatment. Mexate 5mg tablet can cause serious side effects even at low doses; therefore, regular follow-ups and routine laboratory tests are necessary as a precaution. Do not use this medicine if you are pregnant, breastfeeding, or planning to become pregnant.

To treat certain types of cancers To treat severe psoriasis To treat rheumatoid arthritis

Mexate 5mg tablet inhibits dihydrofolic acid reductase. Therefore, this medicine interferes with DNA synthesis, repair, and cellular replication. Actively proliferating tissues such as malignant cells, bone marrow, fetal cells, buccal and intestinal mucosa, and urinary bladder cells are, in general, more sensitive to this medicine. Blocking these slows down how fast cancer cells grow and spread. In treating rheumatoid arthritis, this medicine is thought to stop or reduce inflammation in the joints by altering the body's defense mechanism in the immune system.

Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, your physician decides the dose, dosage, and frequency of this medicine. Do not chew, crush or dissolve the tablets. The score line is only there to help you break the tablet if you have difficulty swallowing it whole. Swallow the tablets whole with water.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Hairloss Photosensitivity Rash Diarrhea, Nausea and Vomiting Decreased WBC and platelet count Dizziness Tiredness, fever, and shivering Blurred vision Serious Severe allergic reactions Spitting or coughing blood Chest pain Weakness on one side of the body Muscle weakness

Avoid getting vaccines while using this medicine. This drug can cause sun sensitivity, so use sunscreen when going outdoors. Mexate 5mg tablet affects male and female infertility; consult your doctor before initiating the treatment if this concerns you. Male patients with female partners with reproductive potential should use an effective form of birth control during the treatment and 3 months after the last dose. Do not consume alcohol while receiving this medicine because this may increase the risk of liver damage. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Inform your physician if you develop sores or white patches on your lips, mouth, or throat while using this medicine.