Midostar 25mg Capsule

Midostar 25mg capsule contains midostaurin, a tyrosine kinase inhibitor used in cancer treatment. It is used together with other chemotherapy medicines to treat acute myeloid leukaemia (AML) in adults with FLT3 gene mutations. Acute myeloid leukaemia is a cancer originating in myeloid cells, a type of white blood cell, where the body produces these cells abnormally in excess. The medicine is also used in adults for aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL).

Do not take Midostar 25mg capsule if you are allergic to midostaurin or any other ingredient in this medicine. Inform your healthcare professional if you have symptoms of infection, heart disorder, lung problems, or breathing difficulties. If you experience fever, sore throat, mouth ulcers, cough with or without mucous, chest pain, difficulty breathing, or body swelling after taking this medicine, report these symptoms to your doctor immediately. This medicine is not recommended for children and adolescents under 18 years of age.

Inform your physician if you are pregnant, breastfeeding, or planning pregnancy before beginning treatment. Midostar 25mg capsule may reduce fertility in men and women; discuss this with your doctor before starting therapy. The most common side effects are fever accompanied by reduced blood cell counts, nausea, vomiting, headache, musculoskeletal pain, elevated blood glucose levels, and respiratory tract infection.

Midostar 25mg Capsule is used in the treatment of the following: Acute myeloid leukemia (AML) Aggressive systemic mastocytosis (ASM) Systemic mastocytosis with associated hematological neoplasm (SM-AHN) Mast cell leukemia (MCL)

Midostar 25mg capsule is a kinase inhibitor that potently inhibits multiple receptor tyrosine kinases. It blocks the action of the kinases in the abnormal cells that express FLT3 mutant genes and stops their division and growth.

Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Take the Midostar 25mg capsule as prescribed by your doctor. Do not open, break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take the capsules with food at the same time each day.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common side effects of Midostar 25mg Capsule are: Swelling in the lower limbs Skin rash Increased blood sugar levels Abdominal pain Constipation, diarrhoea Nausea, vomiting Musculoskeletal pain Headache Bleeding from nose Upper respiratory infection Tiredness Fever Serious side effects of Midostar 25mg Capsule are: Heart failure GI bleeding Fever with decreased blood cell counts Hypersensitivity reactions Kidney problems Pneumonia Blood infection

Do not breastfeed during the treatment with Midostar 25mg capsule and for at least 4 months after the last dose. Avoid grapefruit juice during the treatment with this medicine. If you vomit after taking this medicine, do not take another capsule to make up the dose. If you are a male patient with a female partner with reproducing potential, use effective contraception during the treatment and for 4 months after the last dose. Your doctor will perform regular blood tests during the treatment to monitor the number of blood cells and electrolytes in your body. Your heart and lung function will also be checked regularly. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.