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Mirel 18mg Injection

Salt Composition: RETEPLASE

₹19619.00₹29500.00

Inclusive of all taxes

Categories: Cardiology

Conditions: Anticoagulants

Product Introduction

Mirel 18mg injection contains reteplase, a tissue plasminogen activator that breaks up blood clots and restores blood flow. It is used to dissolve a blood clot causing acute myocardial infarction within 12 hours of symptom onset. This medicine carries a risk of excessive bleeding and must be administered only by a doctor. Patients taking heparin and aspirin (acetylsalicylic acid) should inform their doctor before starting any new medication to prevent increased bleeding risk. Individuals with brain disorders, bleeding disorders, high blood pressure, or kidney and liver disorders should exercise caution and speak with their doctor before taking Mirel 18mg injection. Inform your doctor if you have undergone major surgery within the past three months. Elderly patients aged 75 years and above should consult their doctor before taking this medicine. Notify your doctor if you are pregnant or breastfeeding. Although no clinical evidence exists regarding passage of the drug through breast milk, it is advisable to inform your doctor to avoid any potential adverse effects.

Uses

Heart attack

How it works

The main activity of the drug is to increase the breakdown of the blood clot by increasing the breakdown of the blood clotting enzyme(plasminogen).

How to Use

The dosage and frequency of Mirel 18mg injection administration are determined depending on the severity of your disease and other considerations by the healthcare provider.

Side Effects

Common Bleeding at the injection site Pain in chest Low blood pressure Shortness of breath Burning sensation Bleeding in the digestive tract (blood vomiting), urinary tract, gums Abnormal heart function (arrhythmias)

Expert Tips

Before taking the medication, it's essential to discuss your medical history if you have a bleeding disorder, stomach or small intestine ulcers, enlarged blood vessels in the food pipes, or high blood pressure. The blood pressure of the patient should be monitored before administering the medicine to avoid complications caused by the drug. You can apply gentle pressure to avoid bleeding at the injection site.

References

  1. Actavis Italy S.p.A, Electronic medicines compendium (emc),[Revised on February 2006][ Accessed Sep2023], https://www.ema.europa.eu/en/documents/product-information/rapilysin-epar-product-information_en.pdf
  2. Reliance lifescience; [Accessed on 12/09/2023]; https://www.rellife.com/web/lifesciences/mirel
  3. KD Tripathi, Essentials of Medical Pharmacology, Adrenergic system and drugs, 7th edition, 2013, 134.
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Blood coagulation and anticoagulant, fibrinolytic, and antiplatelet drugs, 12th edition, 2011, 866.

Safety Advice

Pregnancy: Consult your doctor Consult your healthcare provider if you plan to get pregnant. However, the medication has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.

Lungs: Consult your doctor It is unknown whether Mirel 18mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor It is unknown whether Mirel 18mg injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS