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Mistabron 200mg Injection

Salt Composition: MESNA

₹1304.00₹1630.25

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Mistabron 200mg injection contains the active substance mesna. It is a cytoprotective drug that belongs to the class of haemorrhagic cystitis inhibitors. This medicine reduces the risk of haemorrhagic cystitis (a condition that causes bladder inflammation and can result in serious bleeding) in patients who receive ifosfamide (a medication used for treating cancer). It protects against some of the harmful effects of certain chemotherapy medications. Do not take this injection if you are allergic to mesna or any other ingredients of this medicine. This medicine can cause serious allergic reactions and skin reactions. Inform your doctor if you experience any symptoms of fever, swelling of your face, lips, mouth, or tongue, difficulty breathing or wheezing, itching, burning, skin rash or hives, skin redness, or swelling after taking this medicine. Notify your physician if you are pregnant or breastfeeding or have severe liver and bladder problems. Female patients should use effective contraception during treatment with Mistabron 200mg injection in combination with other anticancer medication and for 6 months after the last dose. The most common side effects are nausea, vomiting, constipation, decreased platelet and white blood cell levels, tiredness, fever, abdominal pain, headache, hair loss, and difficulty sleeping.

Uses

Hemorrhagic cystitis

How it works

Mistabron 200mg injection reduces ifosfamide (cancer medication) induced hemorrhagic cystitis by binding to certain metabolites, inhibiting their toxic effects on the bladder.

How to Use

It should only be administered by a trained doctor or nurse experienced in administering chemotherapy. The medicine will be given as an infusion into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Chest pain Swelling in the face, feet, and hands Hair loss Excessive sweating Decreased potassium levels Abdominal pain Constipation Diarrhea, loss of appetite Nausea, vomiting Anemia Changes in the blood count levels Backache Confusion, dizziness, headache Fever, tiredness Serious Rash Hypersensitivity reactions

Expert Tips

Drink more fluids so you will urinate more often and help prevent kidney problems. Drink 1 to 2 liters of fluid each day. Male patients with female partners should use an effective form of birth control during treatment and for 3 months after the last dose. Do not breastfeed during the treatment with this medicine and for 1 week after the last dose. Your physician may take regular lab tests to check for the effectiveness of the therapy and monitor you for any unwanted effects of the medicine.

References

  1. HIGHLIGHTS OF PRESCRIBING INFORMATION - Mesna [revised on 2014] [cited 2023 Apr 6]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/019884s013lbl.pdf
  2. Boehringer-Ingelheim, Mesna [Revised on March 2014] [ Accessed on 06 April 2023], https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Ben%20Venue_Bedford%20Labs/55390-045-01%20MSN%201G/5539004501
  3. V Reddy, Winston NR; Mesna; NCBI Bookshelf; [Revised on Nov 2020] [Accessed on 06th April 2023], https://www.ncbi.nlm.nih.gov/books/NBK556021/

Safety Advice

Pregnancy: Consult your doctor There are limited human studies on the safety of Mistabron 200mg injection during pregnancy. Consult your doctor if you are pregnant, suspecting, or planning for pregnancy.

Lungs: Consult your doctor It is unknown whether Mistabron 200mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Mistabron 200mg injection because the medicine secrete into the breast milk in small amounts and may harm your baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS