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Mozosted 24mg Injection

Salt Composition: PLERIXAFOR

₹27073.00₹59062.50

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Mozosted 24mg Injection is an antineoplastic agent containing plerixafor. It is indicated for mobilising and collecting blood stem cells prior to autologous transplantation in patients with lymphoma, multiple myeloma, and solid tumours. The medicine enhances stem cell mobilisation into peripheral blood circulation.

Inform your doctor if you have cardiac or renal disorders. Before initiating treatment, disclose to your doctor if you have elevated white blood cell counts, reduced platelet counts, or a history of dizziness or syncope. Do not use this medicine if you have hypersensitivity to plerixafor or any component of the formulation. Do not use this medicine if you are pregnant, planning pregnancy, suspect pregnancy, or are breastfeeding. Report to your doctor immediately if you develop adverse effects including rashes or periocular swelling, altered breathing pattern (hypoxia), or pain in the upper left abdomen or left shoulder region.

Uses

Collecting blood stem cells Lymphoma and multiple myeloma in adults Lymphoma or solid tumors in children (aged between 1 to 18)

How it works

Mozosted 24mg Injection works by blocking a protein called CXCR4 (chemokine receptor) on stem cells, which helps them move from the bone marrow into the bloodstream. By blocking CXCR4, Mozosted 24mg Injection causes the stem cells to be released into the bloodstream, where the stem cells can be collected and isolated using a machine (apheresis) and stored for transplantation.

How to Use

This medicine is given only in a hospital setup by a healthcare provider. Mozosted 24mg Injection will be given to you by your doctor. It is given subcutaneously (under the skin). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Rashes and swelling around the eyes Difficulty in breathing Faintness Upper left abdomen pain Left shoulder pain Common Diarrhea Vomiting Redness or irritation in the injection site Low RBC count (anemia) Feeling tired Constipation, indigestion Dry mouth, numbness (around the mouth) Joint pains Pain in muscle and bones Sweating Stomach symptoms (pain, swelling or discomfort) Difficulty in sleeping Headache

Expert Tips

Your doctor may also perform regular blood tests to monitor the blood cell count. Drink enough water or take electrolytes to compensate for the water loss caused by vomiting. Avoid fatty foods (oil, butter, and red meat) and include high-fiber content foods to overcome constipation and indigestion caused by the drug.

References

  1. Genzyme Corporation, U.S. Food & Drug Administration [Revised on Aug 2020] [Accessed on 13th Feb 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022311s022lbl.pdf
  2. EUROAPI UK Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2022] [Accessed on 13th Feb 2024]], https://www.medicines.org.uk/emc/files/pil.790.pdf
  3. James L. Zehnder, Agents Used in Cytopenias; Hematopoietic Growth Factors, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 591- 607.

Safety Advice

Pregnancy: Consult your doctor It is unknown whether Mozosted 24mg Injection is harmful to the unborn baby. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.

Lungs: Consult your doctor It is unknown whether Mozosted 24mg Injection is safe for patients with lung problems. Inform your physician if you have any liver disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: Consult your doctor It is unknown whether Mozosted 24mg Injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS