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Mycomune 500mg Tablet

Salt Composition: MYCOPHENOLATE MOFETIL

₹527.00₹789.00

Inclusive of all taxes

Categories: Cardiology

Conditions: Transplant

Product Introduction

Mycomune 500mg Tablet is an immunosuppressant containing mycophenolate mofetil as its active ingredient. It functions as an inosine monophosphate dehydrogenase (IMPDH) inhibitor. The medication is used to prevent organ rejection in patients who have received an organ transplant, including kidney, heart, or liver transplantation. Treatment is administered as part of combination therapy alongside other immunosuppressive medications.

This drug is contraindicated during pregnancy due to the risk of birth defects and miscarriage. It should not be prescribed in pregnant women unless no suitable alternatives exist and the potential benefits outweigh the risks. Women of childbearing potential are strongly advised to use effective contraception while taking this tablet to prevent pregnancy.

Live vaccines must not be administered to patients taking Mycomune 500mg Tablet due to reduced vaccine effectiveness and increased infection risk. Patients receiving this medication should not donate blood during treatment and for at least six weeks after discontinuation to ensure adequate clearance of the medication from the body.

The medicine should not be taken if you are allergic to mycophenolate mofetil or any other ingredients in the formulation. Inform your doctor of any existing liver or heart disease before commencing treatment. As this drug suppresses the body's immune defences, it increases the risk of skin cancer. Patients must take precautions to limit sunlight and ultraviolet (UV) light exposure.

Seek medical attention immediately if you develop unexplained bruising under the skin, fever, unexplained fatigue, dizziness, yellowing of the skin or eyes, vision changes, reduced urine output, or seizures after taking this medicine.

Mycomune 500mg Tablet is an immunosuppressive medication that may affect the infant's developing immune system and should be avoided during breastfeeding. In some cases, alternative medications with a more favourable safety profile during breastfeeding may be considered.

Uses

Prevent organ transplant rejections.

How it works

Mycomune 500mg Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ

How to Use

It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Mycomune 500mg Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Infections, fever, or sore throat Unusual bleeding or bruising Low blood cell count Severe allergic reactions Common Higher risk of developing lymphoma and other cancers Nausea, abdominal pain Diarrhea Constipation Loss of appetite Shortness of breath Weight loss Increased heartbeat Headache Blood pressure problem Anaemia

Expert Tips

It is necessary to take the prescribed dose exactly as instructed by your doctor. Inform your doctor about all the medications (prescription, over-the-counter, and herbal) you are taking, as they can interact with this drug. If you plan to conceive or suspect you might be pregnant while taking Mycomune 500mg Tablet, it is important to consult your doctor immediately. They may suggest switching to alternative medications that are safer during pregnancy or adjusting your treatment plan.

References

  1. Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
  2. Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
  3. S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
  4. KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
  5. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.

Safety Advice

Pregnancy: unsafe Mycomune 500mg Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.

Lungs: Consult your doctor Mycomune 500mg Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.

Breastfeeding: unsafe Mycomune 500mg Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS