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Nab Pacliage Injection
Salt Composition: PACLITAXEL,HUMAN ALBUMIN
- Manufacturer: AEGIS PHARMACEUTICALS
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Prescription Required
- Storage: Store at 20â25°C in a cool, dry place away from direct sunlight. Contact your healthcare provider immediately if you miss a dose; do not self-adjust the schedule. Seek emergency medical attention if an overdose is suspected. Keep Nab Pacliage Injection out of reach of children.
₹3047.00₹12187.50
Inclusive of all taxes
Product Introduction
Nab Pacliage Injection is a specialised formulation combining the anti-cancer drug paclitaxel with human albumin, a protein naturally found in the body. This combination belongs to the therapeutic class of antineoplastic agents and is used to treat various cancers, including metastatic breast cancer, non-small cell lung cancer (NSCLC), and advanced pancreatic cancer. By using human albumin, the drug achieves improved solubility and delivery of paclitaxel, enhancing its therapeutic effects whilst reducing solvent-related side effects. Nab Pacliage Injection is administered via intravenous infusion and must be used under the supervision of a qualified healthcare professional. Safety precautions are essential, as the drug is contraindicated in patients with hypersensitivity to its components and those with severe liver impairment. Pregnant and breastfeeding women should avoid this medication due to its potential risks. Warnings associated with Nab Pacliage Injection include myelosuppression (reduced bone marrow activity), risk of infections, and potential nerve damage. Careful monitoring and adherence to dosing schedules are important for treatment outcomes.
Uses
Nab Pacliage Injection is FDA-approved for the treatment of: Metastatic breast cancer Non-small cell lung cancer (NSCLC) Advanced pancreatic cancer
How it works
Paclitaxel, the active ingredient in this formulation, works by disrupting the division and growth of cancer cells. It targets the microtubules within the cells, which are essential for cell division. By stabilizing these structures, the drug prevents cancer cells from completing their lifecycle, leading to cell death. The inclusion of human albumin enhances drug delivery to tumors, making the treatment more effective and reducing side effects commonly associated with traditional solvents.
How to Use
The dose depends on the type and stage of cancer. A healthcare professional will determine the appropriate schedule. Nab Pacliage Injection is administered as an intravenous infusion. It can be taken without regard to meals.
Side Effects
Common Side Effects: Nausea and vomiting Fatigue Hair loss Muscle or joint pain Mild diarrhea Serious Side Effects: Severe allergic reactions (rash, swelling, difficulty breathing) Peripheral neuropathy (numbness or tingling in hands/feet) Neutropenia (low white blood cell count) Severe liver enzyme elevation
Expert Tips
Patients undergoing treatment with Nab Pacliage Injection should follow their doctorâs instructions carefully and attend all scheduled appointments for monitoring. Ensure you inform your healthcare provider about any pre-existing conditions, current medications, or supplements. Stay hydrated and maintain a balanced diet to support overall health during treatment. If any side effects become severe, seek medical attention promptly.
References
- Stinchcombe TE. Nanoparticle albumin-bound paclitaxel: a novel Cremphor-EL-free formulation of paclitaxel. Nanomedicine (Lond). 2007 Aug;2(4):415-23. doi: 10.2217/17435889.2.4.415. PMID: 17716129. https://pubmed.ncbi.nlm.nih.gov/17716129/
- https://pubs.rsc.org/en/content/articlelanding/2014/md/c4md00200h
- https://www.cancer.gov/publications/dictionaries/cancer-terms/def/paclitaxel-albumin-stabilized-nanoparticle-formulation
Safety Advice
Pregnancy: unsafe Nab Pacliage Injection can harm the unborn baby and should not be used during pregnancy unless absolutely necessary.
Lungs: Consult your doctor Patients with pre-existing lung issues should discuss their condition before starting treatment, as it may exacerbate breathing difficulties.
Breastfeeding: unsafe Breastfeeding is not recommended while taking Nab Pacliage Injection as the drug can pass into breast milk and harm the infant.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.