Nelova 150mg Capsule

Nelova 150mg Capsule is an antineoplastic drug containing the active ingredient Nilotinib. It belongs to the class of tyrosine kinase inhibitors. This medicine is used to treat Philadelphia chromosome-positive chronic myeloid leukaemia (Ph-positive CML), a blood cancer characterised by abnormal production of white blood cells. In adult and paediatric patients, it is indicated in those newly diagnosed with chronic myeloid leukaemia (CML) and those experiencing side effects from previous treatment. It is also used in patients with CML who no longer respond to previous treatment, including Imatinib.

Do not take this medicine if you are allergic to Nilotinib or any other ingredients in this medicine. Notify your doctor if you have or have had a history of heart conditions (heart attack, abnormal electrical signal), chest pain, brain stroke, or claudication (a condition affecting blood flow in the legs). Inform your doctor if you have liver or pancreatic disorder, or are suffering from a deficiency of potassium or magnesium. Tell your doctor about all medications you are taking, especially those used to lower blood cholesterol. Inform your doctor of your underlying conditions, particularly if you have or have ever had hepatitis B infection; this medicine can reactivate hepatitis B, which can be fatal in some cases. Avoid consuming grapefruit or grapefruit juice. Inform your doctor if you are intolerant to certain sugars, as this medicine contains lactose.

During treatment, your doctor may conduct regular blood tests to monitor liver and pancreatic function and the number of blood cells (white blood cells, red blood cells, platelets). Monitoring will also include heart condition (prolongation of the QT interval), electrolytes, and levels of glucose and fats to assess how Nelova 150mg is tolerated. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Use effective birth control during treatment with this medicine.

Blood cancer (Philadelphia chromosome-positive chronic myeloid leukemia) in adults and pediatrics.

BCR-ABL tyrosine kinase is responsible for the uncontrolled division of cells in the CML. Nelova 150mg disrupts the signaling route of the protein kinase enzyme which targets the BCR-ABL protein and inhibits the growth and spread of cancer cells.

Take Nelova 150mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking Nelova 150mg unless your doctor advises you to stop.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Sudden weight gain Swelling in hands, feet, ankles, or face Chest pain Blood pressure (high and low) Discoloration of tongue, lips, or skin (blue) Abnormal heart (irregular heartbeat) Hair loss Vision problem Stomach pain, vomiting of blood, blood in stools. Yellowing of the skin, eyes, and dark urine. High blood sugar levels. Sensitivity to light Common Nausea, vomiting, diarrhoea. Headache, muscle pain, stomach pain. Hair loss. Tiredness. Constipation. Slowing of growth in children. Pneumonia. Loss of appetite. Sleeplessness, depression, and anxiety. Stomach discomforts like bloating and flatulence after meals. musculoskeletal pain

Based on your condition your doctor may prescribe a lower dose. Nelova 150mg can be used by people aged 65 years and over with the same dose as other adults. Tell your doctor if you experience any irregular heartbeats or any signs of a heart condition because this can lead to serious complications like sudden death. Inform your physician if you have kidney problems. Your physician will decide whether you may receive this medication after monitoring your kidney functions. Some children and adolescents taking this medicine may have slower than normal growth. So, your doctor will regularly monitor your growth. Report to your doctor if you have had a history of heart failure or hepatitis infection. Discuss effective contraceptive options with your healthcare provider.