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Nevilast 40mg Tablet

Salt Composition: LAMIVUDINE,NEVIRAPINE,STAVUDINE

₹180.00₹225.00

Inclusive of all taxes

Categories: Infectious Disease

Conditions: Antiviral

Product Introduction

Nevilast 40mg tablet contains the active ingredients Lamivudine, Nevirapine, and Stavudine. This is a combination of three antiretroviral medicines used to treat HIV-1 infection. Lamivudine and Stavudine are nucleoside/nucleotide reverse transcriptase inhibitors. Nevirapine is a non-nucleoside reverse transcriptase inhibitor.

Do not take Nevilast 40mg tablet if you are allergic to Lamivudine, Nevirapine, Stavudine, or any other ingredients in this medicine. Do not take this tablet if you are pregnant or breastfeeding.

Inform your physician before taking this medicine if you have liver problems, hepatitis infection, kidney disease, or if you are undergoing dialysis. Notify your physician if you have any active skin conditions such as rash.

Uses

HIV-1 Infection

How it works

Nevilast 40mg tablet is a combination of three anti-retroviral medicines. Lamivudine and stavudine tablet works by inhibiting the reverse transcriptase enzyme of HIV, restricting the replication of the viral genome, and reducing the production of new infectious viral particles. It mainly interferes with reverse transcription and inhibits the spread of HIV. Nevirapine binds directly to reverse transcriptase (RT) and blocks RNA-dependent and DNA-dependent polymerase activities by causing disruption of the enzyme

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of Nevilast 40mg tablet based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with a glass of water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Decreased red/white blood cells Liver injury Severe skin reaction Common Skin rash Nausea, vomiting Loss of Apetite Diarrhea Abdominal pain

Expert Tips

Follow your doctor’s instructions with respect to high-risk activities such as unprotected sex and personal items that can have blood or body fluids on them, like toothbrushes, razor blades, and needles. Always practice safe sex by using condom to lower the chance of sexual contact with semen, vaginal secretions, or blood. These medications do not cure HIV or AIDS and you can still transmit the virus to other during therapy with these medications.

References

  1. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  2. Sharon Safrin, Antiviral Agents, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 863-894.
  3. Lamivudine, Stavudine and Nevirapine Tablets (Lamivudine 150 Mg, Stavudine 30 Mg and Nevirapine 200 Mg) .; Revised 2010. Accessed May 18, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022177PI.pdf
  4. Siegfried N, van Deventer PJ, Mahomed FA, Rutherford GW. Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults. Cochrane Database of Systematic Reviews . Published online April 19, 2006. doi: https://doi.org/10.1002/14651858.cd004535.pub2

Safety Advice

Pregnancy: unsafe Do not take Nevilast 40mg tablet if you are in your first trimester because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is unknown whether Nevilast 40mg tablet is safe to be administer in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Nevilast 40mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS