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Nindanib 150mg Capsule

Salt Composition: NINTEDANIB

₹865.00₹1108.59

Inclusive of all taxes

Nindanib 150mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Nindanib 150mg capsule contains the active ingredient nintedanib. Substitute brands include Nintena 150. It is a tyrosine kinase inhibitor indicated for idiopathic pulmonary fibrosis, chronic fibrosing interstitial lung disease, and systemic sclerosis-associated interstitial lung disease.

Inform your doctor if you are taking blood thinning medications or have had recent surgery. Use effective contraception during treatment and for three months after the final dose. Birth control pills may not work properly in women taking this capsule; discuss contraceptive options with your doctor.

Before starting treatment, inform your doctor of any medical conditions, including liver and heart problems. Your doctor may conduct liver function tests at regular intervals during the first three months of treatment. Notify your doctor if you have a history of bleeding or blood clots (arterial thromboembolic events).

Nindanib 150mg may cause hepatic impairment and embryo-fetal toxicity. Discuss any existing conditions with your doctor before commencing treatment.

Common side effects include nausea, vomiting, diarrhoea, fever, skin ulcers, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss, and hypertension. Inform your doctor immediately if you experience any side effects.

Uses

Tab Nindanib 150 uses Idiopathic pulmonary fibrosis. Chronic fibrosing lung diseases with a progressive phenotype Systemic sclerosis

How it works

Nindanib 150mg works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.

How to Use

Take Nindanib 150mg as advised by your physician. Swallow the medicine with a glass of water. Do not crush, chew, or open the medicine. Your doctor will decide the correct dose and duration for you based on your age, body weight, and disease condition. Do not stop taking this medicine unless your doctor advises you to stop.

Side Effects

Nindanib 150 Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Bronchitis Myocardial infarction Bleeding problems Pneumonia Major bleeding Yellow eyes, dark urine, pain in the upper right side of the stomach Severe stomach cramps, bloating, fever, and chills Chest pressure or pain on the left side of the body Increased protein in the urine (proteinuria) Common Nausea, vomiting, diarrhea Fever Skin ulcer Gastrointestinal perforation Altered liver function values Decreased appetite Headache Weight loss Hypertension

Expert Tips

Inform your physician if you have bleeding problems, hypertension, heart problems or weak blood vessels. Inform your physician if you experience allergic reactions to Nindanib 150mg. Notify your physician if you have recently undergone surgery as this medicine affects the process of wound healing. Consult your physician and use an effective method of contraception while on this treatment and even after the treatment for three months. Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor. Avoid smoking while taking this medicine because it may reduce the effectiveness of the medicine.

References

  1. Boehringer Ingelheim Pharmaceuticals. Inc, [Revised on Oct 2022] [Accessed on 05th April 2023], https://content.boehringer-ingelheim.com/DAM/f0e91cee-803b-4767-8360-af1e011fc97a/ofev-us-ppi.pdf
  2. Boehringer Ingelheim, Electronics Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 05th April 2023], https://www.medicines.org.uk/emc/files/pil.1786.pdf
  3. Boehringer Ingelheim, U.S. Food and Drug Administration, [Revised on Mar 2020], [Accessed on 05th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/205832s013lbl.pdf
  4. Lutz Wollin et al., Mode of action of Nintedanib capsule in the treatment of idiopathic pulmonary fibrosis, Eur Respir J. 2015 May; 45(5): 1434–1445. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416110/

Safety Advice

Pregnancy: unsafe Nindanib 150mg is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.

Lungs: Consult your doctor Consult your doctor if you experience symptoms like pneumonia or any other lung related condition while taking Nindanib 150mg .

Breastfeeding: unsafe Taking Nindanib 150mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS