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Nintena 150mg Capsule

Salt Composition: NINTEDANIB

₹865.00₹1017.66

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Nintena 150mg Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Nintedanib 150mg capsule is a tyrosine kinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, chronic fibrosing interstitial lung disease, and systemic sclerosis-associated interstitial lung disease.

Inform your doctor if you are taking blood thinning medications or have recently undergone surgery. Effective contraception is required during treatment and must be continued for three months after the final dose. Consult your doctor regarding suitable contraceptive options, as oral contraceptives may not be adequately effective in women receiving this medication.

Before beginning treatment, disclose any medical conditions to your doctor, particularly liver and heart disorders. Your doctor may conduct liver function tests at regular intervals during the initial three months of treatment. Notify your doctor of any history of bleeding or blood clots (arterial thromboembolic events).

Nintedanib 150mg may cause hepatic impairment and embryo-fetal toxicity. Inform your doctor if you have any underlying conditions that may be relevant.

Common adverse effects include nausea, vomiting, diarrhoea, fever, skin ulceration, gastrointestinal perforation, altered liver function values, decreased appetite, headache, weight loss, and hypertension. Inform your doctor immediately if you experience any side effects.

Uses

Nintena 150mg uses are: Idiopathic pulmonary fibrosis. Chronic fibrosing lung diseases with a progressive phenotype Systemic sclerosis

How it works

Nintena 150mg works by inhibiting receptor multiple tyrosine kinases (RTKs) enzyme that develops and progresses lung fibrosis (scarring). Inhibiting these enzymes reduces the development of fibrous tissue in the lungs.

Side Effects

Nintena 150mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Bronchitis Myocardial infarction Bleeding problems Pneumonia Major bleeding Yellow eyes, dark urine, pain in the upper right side of the stomach Severe stomach cramps, bloating, fever, and chills Chest pressure or pain on the left side of the body Increased protein in the urine (proteinuria) Common Nausea, vomiting, diarrhea Fever Skin ulcer Gastrointestinal perforation Altered liver function values Decreased appetite Headache Weight loss Hypertension

References

  1. Boehringer Ingelheim Pharmaceuticals. Inc, [Revised on Oct 2022] [Accessed on 05th April 2023], https://content.boehringer-ingelheim.com/DAM/f0e91cee-803b-4767-8360-af1e011fc97a/ofev-us-ppi.pdf
  2. Boehringer Ingelheim, Electronics Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 05th April 2023], https://www.medicines.org.uk/emc/files/pil.1786.pdf
  3. Boehringer Ingelheim, U.S. Food and Drug Administration, [Revised on Mar 2020], [Accessed on 05th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/205832s013lbl.pdf
  4. Lutz Wollin et al., Mode of action of Nintedanib capsule in the treatment of idiopathic pulmonary fibrosis, Eur Respir J. 2015 May; 45(5): 1434–1445. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416110/

Safety Advice

Pregnancy: unsafe Nintena 150mg is unsafe to use during pregnancy as it may cause birth defects or death to the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant, or planning for the pregnancy before starting the treatment.

Lungs: Consult your doctor Consult your doctor if you experience symptoms like pneumonia or any other lung related condition while taking Nintena 150mg .

Breastfeeding: unsafe Taking Nintena 150mg while breastfeeding may be unsafe because it may affect the child. Therefore, talk with your doctor to get more information.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS