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Nitrol 20mg Injection
Salt Composition: MITOXANTRONE
- Manufacturer: NEON LABORATORIES LTD
- Pack Size: 1 VIAL(s) OF 10ML
- Dosage Form: INJECTION
- Strength: 20MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store vials between 15 and 25 degrees C (59 and 77 degrees F). Do not freeze Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
₹426.00₹532.03
Inclusive of all taxes
Product Introduction
Nitrol 20mg Injection contains the active constituent Mitoxantrone. It belongs to the class of medications called anthracene diones. It is indicated for reducing neurologic disability and the frequency of clinical relapses in patients with secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. It is also combined with other medicines to treat patients with pain related to advanced hormone-refractory prostate cancer. It is also indicated in the initial therapy of acute nonlymphocytic leukaemia (ANLL) in adults. Do not take Nitrol 20mg Injection if you are allergic to Mitoxantrone or any of the other ingredients. Inform your physician if you have bronchial asthma, liver disorders, kidney disorders, heart problems, infections, or have had chest radiotherapy before taking this medicine. This medicine may cause a blue-green coloration to the urine for 24 hours after administration. Bluish discoloration of the whites of your eyes, skin, and nails may also occur. This medicine may increase the risk for the temporary or persistent absence of menstruation in women of childbearing age. Vaccinations and immunisations may not work during treatment with this medicine.
Uses
Advanced-stage of breast cancer Pain caused by prostate cancer at an advanced stage Non-Hodgkinâs lymphoma (cancer of the lymphatic system, a part of the immune system Acute myeloid leukemia and chronic myeloid leukemia (blood cancers) Multiple sclerosis where no alternative therapeutic options exist
How it works
Nitrol 20mg injection, an antineoplastic drug, is a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA), causing crosslinks and strand breaks in DNA through hydrogen binding. It also interferes with ribonucleic acid (RNA) and inhibits topoisomerase II, an enzyme responsible for repairing and uncoiling damaged DNA.
How to Use
Nitrol 20mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age. This medicine will be given intravenously (into your vein). Do not self-administer the injection.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Diarrhea Nausea Vomiting Decreased hemoglobin count Decreased WBC count Headache Urinary tract infection Menstruation problem Serious Heart problems Infection Liver injury
Expert Tips
If the medicine gets in your eyes, rinse your eyes with large amounts of water, and tell your doctor. It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Inform your physician if you have liver disease, anemia, blood clotting problems, bone marrow problems, low white blood cell counts, bleeding problems, or any kind of infection. This medicine may change the color of your urine to bluish-green. The whites of your eyes may also appear slightly bluish-green. This is normal, especially within the first 24 hours after you receive the medicine. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Your doctor may also want to check your heart while you are using this medicine.
References
- EMD Serono, Inc, US Food and Drug Administration, [Issued on Aug 2008] [ Accessed on 06 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019297s030s031lbl.pdf
- LE Posner; Mitoxantrone: an overview of safety and toxicity; Investigational New Drugs; Published on 1985; Accessed on 06 May 2023; https://pubmed.ncbi.nlm.nih.gov/3894276 /
Safety Advice
Pregnancy: unsafe Do not take Nitrol 20mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Lungs: Consult your doctor It is unknown whether Nitrol 20mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Nitrol 20mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.