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Nuace Tablet

Salt Composition: DARUNAVIR,RITONAVIR

₹6074.00₹8099.05

Inclusive of all taxes

Nuace Tablet

Categories: Infectious Disease

Conditions: Antiviral

Product Introduction

Nuace Tablet contains the active ingredients Darunavir and Ritonavir. It is a combination of antiretroviral drugs belonging to the class of protease inhibitors. It is used to treat HIV infection by enhancing immunity in adults and children aged three years and older. However, this medicine does not cure HIV, but may reduce the risk of developing acquired immunodeficiency syndrome (AIDS) and HIV-related conditions. Do not take Nuace Tablet if you are allergic to Darunavir, Ritonavir, or any other ingredients in this formulation. Inform your doctor if you have liver diseases, such as hepatitis B or C infection. Notify your doctor if you have diabetes, as this medicine may increase blood sugar levels. Contact your doctor immediately if you experience any symptoms of infection (enlarged lymph nodes and fever), musculoskeletal problems (joint aches, stiffness, and pain, particularly in the hip, knee, and shoulder), or difficulty with movement. Inform your doctor if you are 65 years or older. Inform your doctor if you are pregnant, suspect you may be pregnant, or are planning to become pregnant before starting treatment with this medicine. Use effective contraception during treatment. Common side effects of this medicine include swelling in the face and feet, rash, abdominal pain, diarrhoea, nausea, vomiting, back pain, and dizziness. Inform your doctor if you experience any of these symptoms for an extended period.

Uses

HIV infection

How it works

Nuace Tablet Tablet is an antiviral combination of medicine that belongs to the category of protease inhibitors. The protease enzyme forms the final protein structure of the HIV. Darunavir and Ritonavir work by inhibiting the action of protease enzymes and leads to the formation of HIV proteins with poor morphology. This, in turn, stops the replication of the virus.

How to Use

It is an orally available prescription drug. Your doctor will decide the dose and duration of Nuace Tablet based on the disease condition and other factors such as body weight and age. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with a glass of water.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Heart problems Severe skin reactions Pancreatitis Increased risk of bleeding Liver problems Diabetes Common Skin rash Nausea, vomiting Swelling in the face and body Abdominal pain, diarrhea Back pain Dizziness Cough, pain in throat

Expert Tips

Discuss effective contraception methods with your doctor, along with fertility concerns. Nuace tablet might reduce its effectiveness in contraception; alternative methods of non-hormonal contraception are recommended. Do not stop the medicine until your doctor advises. Regular blood tests are recommended to evaluate your liver function and hepatitis B virus level. Notify your doctor if you experience any serious side effects. You are doctor may change your dose or stop the treatment. Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. your doctor has prescribed at the right time of day and in the correct order. Do not stop using your medicine unless your doctor tells you to. Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

References

  1. Janssen Pharmaceuticals, [Revised on Apr 2022] [Accessed on 20th May 2023], https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/PREZISTA-pi.pdf
  2. AbbVie Corporation, [Revised on 5th Jul 2021] [Accessed on 20th May 2023], https://www.abbvie.ca/content/dam/abbvie-dotcom/ca/en/documents/products/NORVIR_PM_EN.pdf
  3. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  4. Capetti et al., A dual regimen of ritonavir/darunavir plus dolutegravir for rescue or simplification of rescue therapy: 48 weeks’ observational data, BMC Infectious Diseases (2017) 17:658, https://bmcinfectdis.biomedcentral.com/counter/pdf/10.1186/s12879-017-2755-4.pdf

Safety Advice

Pregnancy: Consult your doctor Do not take Nuace Tablet unless your doctor advised to take these tablets because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment.

Lungs: Consult your doctor It is unknown whether Nuace Tablet is safe to be administer in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.

Breastfeeding: Consult your doctor Breastfeeding is not recommended in patients taking Nuace Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS