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Nublexa 40mg Tablet

Salt Composition: REGORAFENIB

₹29572.00₹36965.00

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Nublexa 40mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Nublexa 40 mg tablets contain regorafenib, an active substance used to treat cancer by slowing the growth of cancer cells. These tablets are indicated for patients with colon cancer, rectal cancer, certain types of gastric cancer, bowel cancer, and hepatocellular carcinoma. Inform your doctor before taking this medicine if you have liver disease, a history of or current bleeding disorders, severe gastrointestinal disorders, cardiac conditions, or hypertension. Do not take this medicine if you are allergic to regorafenib.

Uses

Nublexa 40 mg tablet is used in the treatment of: Colorectal cancer has started to spread to other parts of the body Gastrointestinal stromal tumors (GIST) (a type of stomach and bowel cancer) Liver cancer in adult patients who have already undergone treatment with Sorafenib

How it works

Nublexa 40 mg tablets work by slowing down the growth and spread of cancer cells and cutting off their blood supply.

How to Use

Follow the exact dosage prescribed by your doctor. Do not crush, chew or break the tablet. Swallow the tablet as a whole with water. Take the tablet with food.

Side Effects

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them. Severe : Allergic reaction Severe liver problems Bleeding Gastrointestinal perforation Infections Heart attack and severe chest pain Severely high blood pressure Skin eruptions Pancreatitis Skin cancers Confusion, Seizures, headaches, and vision loss with or without high blood pressure Stevens-Johnson syndrome Skin detachment Enlargement of a blood vessel or a tear in a blood vessel Common: Reduced number of white blood cells Hypothyroidism Lowered levels of phosphate, potassium, calcium, sodium, or magnesium Elevated level of uric acid in the blood Dehydration Headache and tremors Disorder of the nerves that causes numbness, tingling, weakness, or pain (peripheral neuropathy) Changes in taste, dry mouth Heartburn Gastroenteritis (inflammation and infection of the stomach) Hair loss (alopecia) Dry skin Rashes Muscle spasms Protein in urine Abnormal blood clotting condition

Expert Tips

Talk to the doctor if the patient has any liver disorders, infection, bleeding problems, stomach and bowel problems, chest pain, heart diseases, high blood pressure, persistent headache, seizures, or recently had or going to have a surgical procedure before taking this medicine. It is not recommended for adolescents and children. Avoid drinking grapefruit juice while taking this medicine, as it can use the effectiveness of the medications. Avoid taking this medicine if the patient is planning for pregnancy or during pregnancy and breastfeeding, as it causes harmful effects on the developing baby.

References

  1. Bayer AG; Electronic Medicines Compendium; [Revised:2019] [Accessed:29/Apr:2021] https://www.medicines.org.uk/emc/files/pil.1263.pdf
  2. TJ Ettrich et al; Regorafenib; [Revised:2014] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/24756792/
  3. Dirk Strumberg; Regorafenib for cancer; [Revised:2012] [Accessed:29/Apr/2021] https://pubmed.ncbi.nlm.nih.gov/22577890/
  4. Bayer HealthCare Pharmaceuticals Inc; US Food And Drug Administration; [Revised:2012] [Accessed:29/Apr/2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203085lbl.pdf

Safety Advice

Pregnancy: unsafe Nublexa 40 mg tablet is not safe to be used during pregnancy. Consult with your doctor for advice.

Lungs: Consult your doctor Nublexa 40 mg tablet should be used with caution in patients with a history of lung disease. Please consult your doctor for more advice.

Breastfeeding: unsafe It is not recommended to breastfeed while taking Nublexa 40 mg tablets. Consult with your doctor for advice.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS