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Ocanat 10mg Tablet

Salt Composition: OBETICHOLIC ACID

₹375.00₹468.75

Inclusive of all taxes

Categories: Hepatology

Conditions: Liver Disease

Product Introduction

Ocanat 10mg Tablet is a gastrointestinal agent belonging to the farnesoid X-receptor agonist category. It contains the active ingredient Obeticholic acid and is primarily used to treat primary biliary cholangitis (PBC). This chronic liver disease results from inflammation and damage to the small bile ducts in the liver, leading to reduced bile flow, liver damage, and potential scarring (fibrosis).

The tablet is contraindicated in individuals with known hypersensitivity or allergy to any ingredient in the medicine. When taken alongside Ocanat 10mg Tablet, the levels of certain medications may increase. Theophylline (used to aid breathing) and tizanidine (used to relieve muscle stiffness and restriction) are examples where your doctor may need to monitor blood levels and adjust dosages if necessary.

Medications such as cholestyramine, colestipol, and colesevelam, which are used to lower blood cholesterol levels, may reduce the effectiveness of this drug. If you are taking these medicines, your doctor will advise you to take this medication at least 4 to 6 hours before or after taking the bile acid-binding resin to allow sufficient time for their separate absorption.

The use of this drug is not recommended in children or adults. Before taking Ocanat 10mg Tablet, consult your physician if you have concerns about complete blockage of bile ducts in your gallbladder or worsening liver health. Your physician will conduct regular blood tests to monitor your liver function.

Itching may occur as a side effect of this drug, and in some cases, it may become severe (intense itching over much of the body). If you experience difficult-to-tolerate itching, your doctor may prescribe additional medications to manage it or adjust your dosage.

This drug is not recommended for use during pregnancy due to lack of sufficient data and experience with its use in pregnant women. As a precautionary measure, pregnant individuals should avoid taking this drug.

Uses

Treatment of primary biliary cholangitis (PBC)

How it works

Ocanat 10mg Tablet activates the farnesoid X receptor (FXR) in the liver. This activation has various beneficial effects, including reducing liver inflammation, promoting bile flow, and slowing down or reversing liver fibrosis. These actions help to manage the symptoms and progression of PBC.

How to Use

Take the Ocanat 10mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Worsening of liver problems ( white of the eyes or yellowing of skin, black, tarry or bloody stools, coughing up or vomiting blood, confusion, slurred speech, mood swings) Severe itching Lower HDL-C (good cholesterol) Common Tiredness Stomach pain, discomfort, constipation Joint pain, mouth, and throat pain Dizziness Fast or irregular heartbeat Fever Dryness, irritation, or redness of the skin Rash Swelling of ankles, hands, or feet Thyroid hormone irregularity

Expert Tips

Inform your physician if you are taking any medicines to lower blood cholesterol levels. Certain cholesterol-lowering medications can interact with Ocanat 10mg Tablet and may affect their effectiveness or increase the risk of side effects. Your physician must be aware of all the medications you are taking to make appropriate adjustments to your treatment plan if necessary.

References

  1. Almac Pharma Services (Ireland) Limited, Electronic medicines compendium (EMC), [Revised on Aug 2022] [ Accessed on 24th August 2023], https://www.medicines.org.uk/emc/files/pil.2561.pdf
  2. Intercept Pharmaceutical Inc, US Food and Drug Administration, [ Revised on Jan 2018] [Accessed on 24th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207999s003lbl.pdf
  3. Bertram G. Katzung, Lange's Basic and Clinical Pharmacology, Drugs Used in treating Gastrointestinal Diseases, 14th Edition, 2018, 1112.

Safety Advice

Pregnancy: unsafe Ocanat 10mg Tablet is not recommended for use during pregnancy due to the lack of sufficient data and experience with its use in pregnant women. As a precautionary measure, pregnant individuals should avoid taking this drug.

Lungs: Consult your doctor It is unknown whether Ocanat 10mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Breastfeeding: Consult your doctor It is unknown if Ocanat 10mg Tablet passes into the breast milk or if it will harm your baby. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS