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Octride Depot 20mg Injection

Salt Composition: OCTREOTIDE

₹16182.00₹20228.00

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Octride Depot 20mg Injection

Categories: Endocrinology

Conditions: Others

Product Introduction

Octride Depot 20mg Injection contains the active substance octreotide. It is a synthetic compound derived from somatostatin, a substance naturally found in the human body that inhibits the effects of certain hormones, such as growth hormones. It is used to reduce the amount of growth hormone produced by patients with acromegaly (a condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features; joint pain; and other symptoms) who cannot be treated with surgery, radiation, or another medication. Octride Injection is also used to control diarrhoea and flushing caused by carcinoid tumours (slow-growing tumours that release natural substances that can cause symptoms) and vasoactive intestinal peptide-secreting adenomas (VIP-omas; tumours that form in the pancreas and release natural substances that can cause symptoms). It is used to prevent complications following surgery of the pancreas gland. Octride Depot 20mg Injection is also indicated to stop bleeding and to protect from re-bleeding from ruptured gastro-oesophagal varices in patients with chronic liver disease. Octride Depot 20mg Injection is used to treat patients with pituitary tumours that produce too much thyroid-stimulating hormone (TSH) when other types of treatment (surgery or radiotherapy) are not suitable or have not worked and after radiotherapy to cover the interim period until the radiotherapy becomes fully effective. Do not use Octride Depot if you are allergic to octreotide or any of the other ingredients of this medicine. Inform your physician if you have gallstones, high or low blood sugar levels, vitamin B12 deficiency, and liver diseases. Octride Depot 20mg Injection may lower your heart rate, and very high doses can cause abnormal heart rhythm, so your doctor may monitor your heart function regularly during treatment. Inform your physician if you are pregnant or breastfeeding before initiating treatment.

Uses

octride injection uses include: To treat acromegaly Relieve symptoms associated with some tumours of the GI tract To prevent complications following surgery of the pancreas gland To treat pituitary tumours that produce too much TSH

How it works

Octride depot 20mg injection acetate, a cyclic octapeptide agent, inhibits growth hormone, glucagon, and insulin more effectively than the natural hormone somatostatin. The drug also reduces growth hormone and IGF-I (somatomedin C) in acromegaly, inhibits gallbladder contractions, reduces bile secretion, and suppresses thyroid stimulating hormone (TSH) secretion.

How to Use

Always use this medicine exactly as your doctor prescribes. Depending on the condition being treated, the octreotide injection dose may involve an infusion of Octride Depot 20mg injection, which can be given by subcutaneous (under the skin) injection, intramuscularly (into the muscle of the buttocks), or intravenously (into a vein). A healthcare professional will always administer intravenous and intramuscular injections. If you are prescribed a subcutaneous injection, your doctor or healthcare professional will explain how to inject the medicine under the skin.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Octreotide injection side effects include: Common side effects of Octride Depot 20mg Injection are: Diarrhea, flatulence Abdominal pain Back pain Tiredness Headache, nausea Serious side effects of Octride Depot 20mg Injection are: Increased heart rate Changes in heart rhythm Increased or decreased blood sugar levels Changes in thyroid levels Vitamin B12 deficiency Gall stones

Expert Tips

Regularly check blood sugar levels and inform your physician if you notice any changes such as increased or decreased blood sugar level. Female patients of reproductive potential use an alternative non-hormonal method of contraception, such as condoms, when the oral form of this medicine is used. This medicine is given as a shot under your skin, into a muscle, or into a vein, based on your condition. This medicine may improve fertility in women and can cause unwanted pregnancies. Talk to your doctor if you have any concerns.

References

  1. Highlights Of Prescribing Information - Octreotide Injection. Access.fda.gov. [Revised 2019 Apr] [cited 2023 May 30]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021008s043lbl.pdf
  2. Octreotide 100 micrograms/1ml Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [Revised April 2022] [cited 2023 May 30]. Available from: https://www.medicines.org.uk/emc/product/373/smpc
  3. Sandostatin LAR 10 mg powder and solvent for suspension for injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. [Revised May 2022] [cited 2023 May 30]. Available from: https://www.medicines.org.uk/emc/product/1038/smpc
  4. Kenneth R. McQuaid, Drugs used in the Treatment of Gastrointestinal Diseases, Lange's Basic and Clinical Pharmacology, 14th Edition, 2018, 1087-1119.
  5. M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 733-796.

Safety Advice

Pregnancy: Consult your doctor Octride depot 20mg injection will only be given during pregnancy if needed. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

Lungs: Consult your doctor It is unknown whether Octride depot 20mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Octride depot 20mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS