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Ontramab 150mg Injection

Salt Composition: TRASTUZUMAB

₹7718.00₹10125.00

Inclusive of all taxes

Ontramab 150mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Ontramab 150mg Injection contains Trastuzumab as its active ingredient and is indicated for HER2-positive breast cancer. In patients with HER2-positive breast cancer, cancer cells express elevated levels of HER2 proteins, which promote rapid tumour development by acting as a growth signal for malignant cells. This medication is also used to treat metastatic gastric cancer with elevated HER2 protein expression. HER2-positive breast cancers are typically more aggressive in nature. The targeted therapy approach works by selectively binding to HER2 proteins responsible for cancer cell growth, development, and spread. Effective contraception must be used during treatment and for at least 7 months after the final dose. Ontramab 150mg Injection is not recommended for patients under 18 years of age, patients with severe breathing difficulties, or patients requiring oxygen therapy. Inform your doctor if you have cardiac conditions, breathlessness, or prior exposure to other cancer treatments. Disclose all medicines you are taking, including supplements and herbal preparations, before commencing treatment with this medication.

Uses

Ontramab 150mg Injection is indicated for its use in the following conditions: Advanced and metastatic breast cancer Metastatic gastric cancer

How it works

The protein called HER2 (human epidermal growth factor receptor 2) is found in abundant amounts on the surface of certain cancer cells, where it stimulates cancer growth. Ontramab 150mg Injection selectively binds to HER2 and stops the growth of cancer cells.

How to Use

Ontramab 150mg Injection shall either be administered before or after surgery. It will be given as an Intravenous infusion for 90 minutes, if well tolerated it shall be administered within 30 minutes for the next doses.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Heart Problems Allergic reactions Kidney problems Breathing difficulties Common Fever Visual disturbances Nose bleeds or runny nose Hair loss Dizziness Nail disorders Weight loss Loss of appetite Bruising Dry mouth Liver inflammation Muscle pain Asthma/ lung disorders

Expert Tips

It is suggested to inform your doctor if you have a history of allergic reactions to Ontramab 150mg Injection to avoid life-threatening complications. If you have a history of lung disorder or breathing problems inform your doctor beforehand before the treatment commencement. Avoid planning for pregnancy and breastfeeding for a minimum of 7 months after the last dose. Monitor your heart parameters regularly during the treatment with Ontramab 150mg Injection as it may impact the functioning of heart.

References

  1. 1. Roche, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 12th July 2022], https://www.medicines.org.uk/emc/files/pil.3856.pdf 2. Genentech Inc, [Revised on Feb 2021] [Accessed on 12th July 2022], https://www.gene.com/download/pdf/herceptin_prescribing.pdf 3. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.

Safety Advice

Pregnancy: unsafe Discuss with your physician before taking this Ontramab 150mg Injection if you are pregnant or think you might be pregnant. Do not take this medicine during the pregnancy unless advised by the doctor to take as it may cause to the unborn baby.

Lungs: Consult your doctor Talk to your doctor if you have any lung conditions before starting treatment with Ontramab 150mg Injection.

Breastfeeding: unsafe Avoid breastfeeding your baby while on the treatment with Ontramab 150mg Injection atleast for at least seven months after the final dose.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS