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Pabreca 125mg Capsule
Salt Composition: PALBOCICLIB
- Manufacturer: LUPIN LTD
- Pack Size: 21 CAPSULE(s) IN A BOX
- Dosage Form: CAPSULE
- Strength: 125MG
- Prescription Required
- Storage: Keep Pabreca 125mg Bottle Of 21 Capsules out of sight and reach of children. Store at 20°C to 25°C.
₹5344.00₹7125.00
Inclusive of all taxes
Product Introduction
Pabreca 125mg Capsule contains palbociclib, a cyclin-dependent kinase inhibitor used in anticancer therapy. It is indicated for the treatment of hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. The medicine is administered in combination with other anticancer medications. Cancer occurs when cells multiply in an uncontrolled and abnormal manner.
Common side effects associated with Pabreca 125mg Capsule include nausea, vomiting, diarrhoea, tiredness, hair loss, dry skin, rash, infections, nose bleed, decreased appetite, low blood cell counts, swelling of lips and mouth, changes in taste, dry eye, blurred vision, and increased tearing. Inform your doctor if any of these side effects persist or cause concern.
Notify your healthcare provider if you have an allergy to palbociclib or any ingredients in this capsule. Prior to treatment initiation, inform your doctor if you have signs of infections (fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to certain sugars. Seek immediate medical attention if you experience dry cough, chest pain, or difficulty breathing, as these may indicate lung inflammation.
Disclose all medications you are taking, including supplements and herbal medicines, before beginning treatment. Use effective birth control during treatment and for at least three weeks after the last dose. This medicine is not recommended for children and adolescents under 18 years of age.
Uses
Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.
How it works
Palbociclib in Pabreca 125mg capsule works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.
How to Use
Pabreca capsule dosage schedule as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.
Side Effects
Pabreca 125 mg capsule side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing
Expert Tips
Avoid grapefruit and St. John's wort : Do not consume grapefruit, grapefruit juice, or any herbal products containing St. John's wort, as they may interfere with the effectiveness of the medication. Use reliable birth control : Women should use effective contraception during treatment and for at least 3 weeks after the final dose. Men should use contraception for at least 14 weeks after the final dose. May affect fertility : This medicine might reduce fertility in both men and women. Talk to your doctor if you are planning to have children. Regular blood tests : Your doctor may order blood tests to monitor how the medicine is affecting your blood cells. Consult your doctor regularly : Report any unusual symptoms or side effects during treatment to ensure safe and effective use of the medicine.
References
- Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022], https://www.medicines.org.uk/emc/files/pil.4449.pdf
- Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
- Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
- Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
Safety Advice
Pregnancy: unsafe It is not recommended to take Pabreca 125mg capsule during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.
Lungs: Consult your doctor It is not unknown whether Pabreca 125mg can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe It is not recommended to take Pabreca 125mg capsule while breastfeeding as it is not known whether it passes into the breast milk.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.