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Palbace 125mg Tablet

Salt Composition: PALBOCICLIB

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Palbace 125mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbace 125mg Tablet is a targeted therapy containing the active constituent palbociclib. It belongs to the group of anticancer medications known as cyclin-dependent kinase inhibitors. Palbace 125 is primarily prescribed for the treatment of hormone receptor-positive, human epidermal growth factor 2 negative advanced or metastatic breast cancer. This tablet is typically administered in combination with other anticancer agents to enhance treatment outcomes. Palbace 125 mg is often used as part of standard treatment regimens for eligible patients with breast cancer. The medicine is available in different pharmaceutical forms, including Palbace 125 mg capsule. Patients with advanced breast cancer may seek information regarding Palbace 125 mg side effects, alternative options, or the availability of generic formulations. For patients unable to tolerate or access palbociclib, healthcare providers may recommend alternative medications.

Uses

palbace 125 mg uses are: Treatment of hormone receptor (HR)-positive. Human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palbace 125mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Palbace 125mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. palbace 125 mg side effects are Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

Expert Tips

Avoid grapefruit, grapefruit juice, and products containing St. John’s wort during Palbace 75mg treatment. Use effective birth control while on treatment: For females → continue for at least 3 weeks after the last dose. For males → continue for at least 14 weeks after the last dose. This medicine may reduce fertility; consult your physician if you have concerns. Your doctor may recommend regular blood tests to monitor the effect of Palbace 125mg Tablet on blood cells.

References

  1. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  2. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  3. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Palbace 125mg Tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult Your Doctor Inform your doctor about lung issues and seek immediate medical help for new or worsening breathing problems while on Palbace.

Breastfeeding: unsafe It is not recommended to take Palbace 125mg Tablet while breastfeeding as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS