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Palbace 75mg Tablet

Salt Composition: PALBOCICLIB

₹16875.00₹21093.75

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Palbace 75mg Tablet

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Palbace 75mg Tablet contains the active ingredient palbociclib, a cyclin-dependent kinase (CDK) inhibitor used in targeted cancer therapy. It is prescribed for patients with hormone receptor-positive, HER2-negative advanced or metastatic breast cancer, often administered in combination with other anticancer medications such as letrozole or fulvestrant. Palbociclib works by slowing cancer cell growth and preventing uncontrolled multiplication. The dosage of palbociclib is determined by your oncologist based on your individual treatment plan. It is typically taken once daily for 21 days followed by a 7-day break, completing a 28-day cycle. Follow your doctor's instructions carefully when taking this medication. During treatment, regular monitoring of blood cell counts is recommended to avoid complications. Common side effects of palbociclib 75mg include nausea, vomiting, tiredness, diarrhoea, loss of appetite, hair thinning, dry skin, mouth sores, taste changes, blurred vision, and low white or red blood cell counts. If any of these effects persist or worsen, inform your healthcare provider.

Uses

Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer.

How it works

Palbace 75mg Tablet works by blocking the protein called cyclin-dependent kinases 4 and 6, which are vital for the division and growth of cells. By blocking these proteins, this medication slows the growth and prevents the cancer cells from spreading.

How to Use

Take Palbace 75mg Tablet exactly as prescribed by your doctor. Take this medication once a day at the same time with food. Swallow this capsule as a whole with a glass of water. Avoid crushing, breaking, or chewing the capsule.

Side Effects

Palbace side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising) Lung inflammation (chest pain, dry cough, or difficulty breathing) Common: Tiredness Hair loss Dry skin, rash Infections Low blood cell counts Decreased of appetite Nausea, vomiting Diarrhea Swelling of lips and mouth Changes in taste Nose bleed Dry eye, blurred vision, increased tearing

Expert Tips

Avoid grapefruit and its juice as well as any preparations containing St. John’s wort during Palbace 75mg treatment. Use effective birth control: Females: During treatment and for at least 3 weeks after the final dose Males: During treatment and for at least 14 weeks after the final dose Palbace 75mg may reduce fertility; discuss potential risks with your doctor if you're planning to have children. Your doctor may recommend regular blood tests to monitor if the medication affects your blood cell counts.

References

  1. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
  2. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022; https://pubmed.ncbi.nlm.nih.gov/26324355/
  3. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022; https://labeling.pfizer.com/ShowLabeling.aspx?id=14029

Safety Advice

Pregnancy: unsafe It is not recommended to take Palbace 75mg tablet during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Lungs: Consult Doctor

Breastfeeding: unsafe It is not recommended to take Palbace 75mg tablet while breastfeeding as it is not known whether it passes into the breast milk.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS